國立台灣大學 醫學工程學研究所

教師研究成果

謝銘鈞 Ming-Jium Shieh

A. 期刊論文(Journal Paper)(2000年迄今)

  1. Chen Jenny L-Y, Chen J-P, Huang Y-S, Tsai Y-C, Tsai M-H, Jaw F-S, Cheng C-H, Kuo S-H, Shieh M-J. Radiosensitization in esophageal squamous cell carcinoma: Effect of polo-like kinase 1 inhibition. Strahlentherapie Und Onkol. 2016 Apr;192(4):260-8.
  2. Ning ST, Lee SY, Wei MF, Peng CL, Lin SY, Tsai MH, Lee PC, Shih YH, Lin CY, Luo TY, Shieh MJ. Targeting Colorectal Cancer Stem-Like Cells with Anti-CD133 Antibody-Conjugated SN-38 Nanoparticles. ACS Appl Mater Interfaces. 2016 Jul 20;8(28):17793-804.
  3. Peng CL, Chen YI, Liu HJ, Lee PC, Luo TY, Shieh MJ. A novel temperature-responsive micelle for enhancing combination therapy. Int J Nanomedicine. 2016 Jul 25;11:3357-69.
  4. Lin WJ, Lee WC, Shieh MJ. Hyaluronic acid conjugated micelles possessing CD44 targeting potential for gene delivery. Carbohydr Polym. 2017 Jan 2;155:101-108.
  5. Lee PC, Lin CY, Peng CL, Shieh MJ. Development of a controlled-release drug delivery system by encapsulating oxaliplatin into SPIO/MWNT nanoparticles for effective colon cancer therapy and magnetic resonance imaging. Biomater Sci. 2016 Nov 15;4(12):1742-1753.
  6. Hsueh YS, Subramaniam S, Tseng YC, Chiang TM, Mestak O, Cheng TK, Kuo TF, Sivasubramanian S, Lin FH, Shieh MJ. In vitro and in vivo assessment of chitosan modified urocanic acid as gene carrier. Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 1):599-606.
  7. Hsueh YS, Chen YS, Tai HC, Mestak O, Chao SC, Chen YY, Shih Y, Lin JF, Shieh MJ, Lin FH. Laminin-Alginate Beads as Preadipocyte Carriers to Enhance Adipogenesis In Vitro and In Vivo. Tissue Eng Part A. 2017 Mar;23(5-6):185-194.
  8. Weng MT, Tung CC, Lee YS, Leong YL, Shieh MJ, Shun CT, Wang CY, Wong JM, Wei SC. Cytomegalovirus colitis in hospitalized inflammatory bowel disease patients in Taiwan: a referral center study. BMC Gastroenterol. 2017 Feb 13;17(1):28.
  9. Chen KC, Hsieh MS, Li YR, Lin YC, Lai HS, Shieh MJ, Chen JS, Young TH. Study of poly-ɛ-caprolactone membranes for pleurodesis. J Formos Med Assoc. 2017 Feb 16. pii: S0929-6646(17)30017-7.
  10. Jenny Ling-Yu Chen, Yuan-Chun Tsai, Ming-Hsien Tsai, Shin-Yu Lee, Ming-Feng Wei, Sung-Hsin Kuo, Ming-Jium Shieh. Prominin-1-Specific Binding Peptide-Modified Apoferritin Nanoparticle Carrying Irinotecan as a Novel Radiosensitizer for Colorectal Cancer Stem-Like Cells. Part. Part. Syst. Charact. 2017 March. Published online.
  11. Win-Li lin, Jia-Yush Yen and Ming-Jium Shieh * et al : Treatable domain and optimal frequency for brain tumors during ultrasound hyperthermia. Int J Radiation Oncology Biol Phys 2000 ; 46: 239-247.(SCI)
  12. Win-Li Lin, Chihng-Tsung Liauh and Ming-Jium Shieh * et al: Theoretical study of temperature elevation at muscle/bone interface during ultrasound hypertnermie. Med Phys 2000; 27: 1131-1140. (SCI)
  13. Win-Li Lin, Wen-Chang Fan and Ming-Jium Shieh * et al: A theoretical study of cylindrical ultrasound transducers for intracavitary hyperthermia. Int. J. Radiation oncology Biol Phys 2000, 46: 1329-1336.(SCI)
  14. Win-Li Lin, Yung-Yaw Chen, and Ming-Jium Shieh * et al: An investigation of power deposition pattern for scanned ultrasound arrays. Biomed Eng Basis Comm 2000; 12: 1-10. (EI)
  15. J-K Jang, T.S. Kou, and Ming-Jium Shieh* : Microcontroller-based EGG recording system. Biomed Eng Appl Basis Comm, 2001; 13 : 226 – 230. (EI)
  16. F.H. Lin, C.H. Jian and Ming-Jium Shieh* et al: A study of purified montmorillonite intercalated with 5-fluorouracil as drug carrier. Biomaterial, 2002; 23: 1981 – 1987. (SCI)
  17. M.J. Shieh , P.S. Lai, T.H. Young: 5-Aminosalicyclic acid permeability enhancement by a pH-sensitive EVAL membrane, J. Membr. Sci. 2002; 204, 237-246. (SCI)
  18. Liang JT, Shieh MJ , Chen CN, Cheng YM, Chang KJ, Wang SM: Prospective evaluation of laparoscopy-assisted colectomy versus laparotomy with resection for management of complex polyps of the sigmoid colon, World J. Surg 2002; 26:377-383. (SCI)
  19. Tsun I Cheng, Jau Min Wong, Cheng Fang Hong, Skye H. Chen, Tsun Jen Cheng, Ming Jium Shieh , Yue Mong Lin, C.Y. Tso and Andrew T. Huang: Colorectal cancer screening in asymptomatic adults: comparison of colonoscopy, sigmoidoscopy and fecal occult blood tests, J Formos Med Assoc; 2002;101: 685-690. (SCI)
  20. Shu Chen Wei, Ming-His Wang, Ming Jium Shieh , Cheng Yi Wang and Jau Min Wong: Clinical characteristics of Taiwanes hereditary non-polyposis colorectal cancer kindreds, J Formos Med Assoc; 2002;101: 206-209. , ( SCI), NSC-89-2315-B-002-028.
  21. Jen Chiang, Ming-Jium Shieh* , Jane Yung-jen Hsu, and Jau-Min Wong: A Medical Decision Support System for Polyp Screening by Using Fuzzy Classification Trees, AMIA (JAMIA Supplement) San Antonio,TX, 2002, (SCI)
  22. Cheng TI, Wong JM, Hong CF, Cheng SH, Chen TJ, Shieh MJ, Lin YM, Tso CY, Huang AT, Colorectal cancer screening in asymptomatic adults: Comparison of colonoscopy, sigmoidoscopy and fecal occult blood tests, J Formos Med Assoc. 2002, 101, 685-690. (SCI)
  23. S.C. Wei, J.M. Wong, M.J.Shieh , C.Y. Wang Safety and Usefulness of Colonfibroscopy in the very Elderly, Biomed Eng Appl Basis Comm, 2002, 14, 31-34. (EI)
  24. Liang JT, Lai HS, Huang KC, Chang KJ, Shieh MJ, Jeng YM, Wang SM, Comparison of medial-to-lateral versus traditional lateral-to-medial laparoscopic dissection sequences for resection of rectosigmoid cancers: Randomized controlled clinical trial, World J. Surg, 2003; 27, 190-196. (SCI)
  25. Chiang IJ, Shieh MJ, Hsu JYJ, and Wong JM, Building a medical decision support system for colon polyp screening by using fuzzy classification trees, Applied Intelligence, 2005, 22, 61-75. (SCI)
  26. PS Lai, TH Young, CY Wang, and MJ Shieh*, In vitro release of hydrocortisone with glycine-immobilized EVAL membrane, Biomed Eng Appl Basis Comm, 17 (2005) 86-90. (EI)
  27. PS Lai, MJ Shieh, CL Pai, CY Wang, and TH Young*, A pH-sensitive EVAL membrane by blending with PAA, J. Membr. Sci., In press (2005)
  28. Lou PJ, Lai PS, Shieh MJ, Macrobert AJ, Berg K, Bown SG, Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization, Int J Cancer. 2006, 119(11), 2692-2698. (SCI)
  29. Fang HY, Tsai KC, Cheng WH, Shieh MJ, Lou PJ, Lin WL, Chen WS, The effects of power on-off durations of pulsed ultrasound on the destruction of cancer cells, Int J Hyperthermia. 2007, 23(4), 371-380. (SCI)
  30. Wang TW, Wu HC, Wang WR, Lin FH, Lou PJ, Shieh MJ, Young TH, The development of magnetic degradable DP-Bioglass for hyperthermia cancer therapy, J Biomed Mater Res A. 2007,83(3), 828-837. (SCI)
  31. Tseng CL, Wang TW, Dong GC, Yueh-Hsiu Wu S, Young TH, Shieh MJ, Lou PJ, Lin FH, Development of gelatin nanoparticles with biotinylated EGF conjugation for lung cancer targeting, Biomaterials. 2007, 28(27), 3996-4005. (SCI)
  32. Lai PS, Lou PJ, Peng CL, Pai CL, Yen WN, Huang MY, Young TH, Shieh MJ★, Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy, J Control Release. 2007, 122(1), 39-46. (SCI)
  33. Lai PS, Pai CL, Peng CL, Shieh MJ, Berg K, Lou PJ, Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization, J Biomed Mater Res A. 2008, 87(1), 147-155. (SCI)
  34. Tseng CL, Wu SY, Wang WH, Peng CL, Lin FH, Lin CC, Young TH, Shieh MJ, Targeting efficiency and biodistribution of biotinylated-EGF-conjugated gelatin nanoparticles administered via aerosol delivery in nude mice with lung cancer, Biomaterials. 2008, 29(20), 3014-3022. (SCI)
  35. Shieh MJ, Peng CL, Lou PJ, Chiu CH, Tsai TY, Hsu CY, Yeh CY, Lai PS, Non-toxic phototriggered gene transfection by PAMAM-porphyrin conjugates, J Control Release. 2008, 129(3), 200-206. (SCI)
  36. Peng CL, Shieh MJ★, Tsai MH, Chang CC, Lai PS, Self-assembled star-shaped chlorin-core poly(epsilon-caprolactone)-poly(ethylene glycol) diblock copolymer micelles for dual chemo-photodynamic therapies, Biomaterials. 2008, 29(26), 3599-3608. (SCI)
  37. Yang SJ, Shieh MJ★, Lin FH, Lou PJ, Peng CL, Wei MF, Yao CJ, Lai PS, Young TH, Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles, Cancer Lett. 2009, 273(2), 210-220. (SCI)
  38. Peng CL, Lai PS, Lin FH, Yueh-Hsiu Wu S, Shieh MJ★, Dual chemotherapy and photodynamic therapy in an HT-29 human colon cancer xenograft model using SN-38-loaded chlorin-core star block copolymer micelles, Biomaterials. 2009, 30(21), 3614-3625. (SCI)
  39. Yang MC, Wang SS, Chou NK, Chi NH, Huang YY, Chang YL, Shieh MJ, Chung TW, The cardiomyogenic differentiation of rat mesenchymal stem cells on silk fibroin-polysaccharide cardiac patches in vitro, Biomaterials. 2009, 30(22), 3757-3765. (SCI)
  40. Tsai KC, Fang SY, Yang SJ, Shieh MJ, Lin WL, Chen WS, Time dependency of ultrasound-facilitated gene transfection, J Gene Med. 2009, 11(8), 729-736.
  41. Tsai KC, Liao ZK, Yang SJ, Lin WL, Shieh MJ, Hwang LH, Chen WS, Differences in gene expression between sonoporation in tumor and in muscle, J Gene Med. 2009, 933-940. (SCI)
  42. Yang MC, Chi NH, Chou NK, Huang YY, Chung TW, Chang YL, Liu HC, Shieh MJ, Wang SS, The influence of rat mesenchymal stem cell CD44 surface markers on cell growth, fibronectin expression, and cardiomyogenic differentiation on silk fibroin - Hyaluronic acid cardiac patches, Biomaterials. 2010, 31(5), 854-862. (SCI)
  43. Yang SJ, Chang SM, Tsai KC, Chen WS, Lin FH, Shieh MJ★, Effect of chitosan-alginate nanoparticles and ultrasound on the efficiency of gene transfection of human cancer cells, J Gene Med. 2010, 12(2):168-179. (SCI)
  44. Shieh YA, Yang SJ, Wei MF, Shieh MJ★, Aptamer-based tumor-targeted drug delivery for photodynamic therapy, ACS Nano. 2010, 4(3), 1433-1442. (SCI)
  45. Yang SJ, Lin FH, Tsai KC, Wei MF, Tsai HM, Wong JM, Shieh MJ★, Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells, Bioconjug Chem. 2010, 21(4), 679-689. (SCI)
  46. Peng CL, Yang LY, Luo TY, Lai PS, Yang SJ, Lin WJ, Shieh MJ★, Development of pH sensitive 2-(diisopropylamino)ethyl methacrylate based nanoparticles for photodynamic therapy, Nanotechnology. 2010, 21(15), 155103. (SCI)
  47. Shieh MJ, Peng CL, Chiang WL, Wang CH, Hsu CY, Wang SJ, Lai PS, Reduced skin photosensitivity with meta-tetra(hydroxyphenyl)chlorin-loaded micelles based on a poly(2-ethyl-2-oxazoline)-b-poly(d,l-lactide) diblock copolymer in vivo, Mol Pharm. 2010, 7(4), 1244-1253. (SCI)
  48. Ke JH, Wei MF, Shieh MJ, Young TH, Design, Synthesis and Evaluation of Cationic Poly(N-substituent acrylamide)s for In Vitro Gene Delivery, J Biomater Sci Polym Ed. 2010. (SCI)
  49. Ke JH, Wei MF, Shieh MJ, Young TH, Imidazole/Poly(ethylene glycol)-Substituted Poly(N-(8-aminooctyl)acrylamide) as Biocompatible and Efficient Gene Carrier, J Biomater Sci Polym Ed. 2010. (SCI)
  50. Yang SJ, Lin FH, Tsai HM, Lin CF, Chin HC, Wong JM, Shieh MJ★, Alginate-folic acid-modified chitosan nanoparticles for photodynamic detection of intestinal neoplasms, Biomaterials. 2011, 32(8), 2174-2182. (SCI)
  51. Shieh MJ, Hsu CY, Huang LY, Chen HY, Huang FH, Lai PS. Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells, J Control Release. 2011. (SCI)
  52. K e, Jin-He; Wei, Ming-Feng; Shieh, Ming-Jium*; Young, Tai-Horng, Design, Synthesis and Evaluation of Cationic Poly(N-substituent acrylamide)s for In Vitro Gene Delivery, Journal of Biomaterials Science, Polymer Edition:Volume 22 , pp.1215-1236(22) , Number 9, 2011(SCI)
  53. Shu-Jyuan Yang, Feng-Huei Lin, Han-Min Tsai, Chia-Fu Lin, Han-Chiang Chin, Jau-Min Wong, Ming-Jium Shieh*,Alginate-folic acid-modified chitosan nanoparticles for photodynamic detection of intestinal neoplasms, Biomaterials:Volume 32, Issue 8, Pages 2174-2182, March 2011(SCI)
  54. Chin-Ling Pai , Ming-Jium Shieh , Pei-Jen Lou , Fei-Hong Huang , Tzu-Wen, Wang and Ping-Shan Lai, Characterization of the Uptake and Intracellular Trafficking of G4 Polyamidoamine Dendrimers, Australian Journal of Chemistry 64(3) 302-308(SCI)
  55. H-M Jan, M-F Wei, C-L Peng, S-J Lin, P-S Lai and M-J Shieh*, The use of polyethylenimine-DNA to topically deliver hTERT to promote hair growth, Gene Therapy (2012) 19, 86–93 (SCI)
  56. Wang CP, Chen TC, Lou PJ, Yang TL, Hu YL, Shieh MJ, Ko JY, Hsiao TY, Neck ultrasonography for the evaluation of the etiology of adult unilateral vocal fold paralysis. Head Neck, 2012, 34(5):643-8
  57. Wang CP, Chen TC, Yang TL, Chen CN, Lin CF, Lou PJ, Hu YL, Shieh MJ*, Hsieh FJ, Hsiao TY, Ko JY , Transcutaneous ultrasound for evaluation of vocal fold movement in patients with thyroid disease. Eur J Radiol, 2012, 81(3):e288-91
  58. Peng CL, Shih YH, Liang KS, Chiang PF, Yeh CH, Tang IC, Yao CJ, Lee SY, Luo TY, Shieh MJ*., Development of in situ forming thermosensitive hydrogel for radiotherapy combined with chemotherapy in a mouse model of hepatocellular carcinoma, Mol. Pharmaceutics, (2013)10 ,1854–1864 (SCI)
  59. Tsai CF, Hsiao CH, Lee JM, Chen KC*, Shieh MJ*, Lai HS, Chen JS., Video-assisted thoracoscopic surgery for recurrent pneumothorax in pulmonary lymphangioleimyomatosis with tuberous sclerosis complex, Journal of Cardiothoracic Surgery, (2013)8, 101
  60. Pei-Chi Lee, Yu-Chi Chiou, Jau-Min Wong, Cheng-Liang Peng, Ming-Jium Shieh*, Targeting colorectal cancer cells with single-walled carbon nanotubes conjugated to anticancer agent SN-38 and EGFR antibody, Biomaterials(2013) 34, 8756-8765. (SCI)
  61. Cheng-Ping Wang, Pei-Jen Lou, Fei-Yun Lo, Ming-Jium Shieh, Meta-tetrahydroxyphenyl chlorine mediated photodynamic therapy inhibits the migration and invasion of a nasopharyngeal carcinoma KJ-1 cell line, Journal of the Formosan Medical Association (2014) 113, 173-178.(SCI)
  62. Yu-Sheng Hsueh, S. Savitha, S. Sadhasivam, Feng-Huei Lin, Ming-Jium Shieh, Design and synthesis of elastin-like polypeptides for an ideal nerve conduit in peripheral nerve regeneration, Materials Science and Engineering : C,38 (2014) 119–126 (SCI)
  63. Jyh-Chin Yang, Chun-Jung Lin, Hong-Long Wang, Jin-De Chen, John Y. Kao, Chia-Tung Shun, Chien-Wei Lu, Bor-Ru Lin, Ming-Jium Shieh, Ming-Chu Chang, Yu-Ting Chang, Shu-Chen Wei, Lin-Chih Lin, Wen-Chun Yeh, Jen-Shin Kuo, Chien-Chih Tung, Yew-Loong Leong, Teh-Hong Wang, Jau-Min Won High-dose Dual Therapy Is Superior to Standard First-line or Rescue Therapy for Helicobacter pylori Infection. Clinical Gastroenterology and Hepatology, 2014, S1542-3565(14).(SCI)
  64. Jyh-Chin Yang, Chun-Jung Lin, Jin-De Chen, Hong-Long Wang, Chia-Tung Shun, Chien-Wei Lu, Bor-Ru Lin, Ming Jium Shieh, Ming-Chu Chang, Yu-Ting Chang, Shu-Chen Wei, Lin-Chih Lin, Wen-Chun Yeh, Jen-Shin Kuo, Chien-Chih Tung, Yew-Loong Leong, Teh-Hong Wang, Jau-Min Wong 564 Efficacy of Optimized High Dose Dual Therapy, Sequential Therapy and Triple Therapy in Helicobacter pylori Eradication—A Prospective, Comparative, Randomized Control Study. Gastroenterology,2014,146(5),P S-103.(SCI)
  65. Ming-Feng Wei, Min-Wei Chen, Ke-Cheng Chen, Pei-Jen Lou, Susan Yun-Fan Lin, Shih-Chieh Hung, Michael Hsiao, Cheng-Jung Yao & Ming-Jium Shieh. Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. Autophagy,2014,10(7),1179-1192 (SCI)
  66. Shu-Chen Wei, Yan-Yin Tan, Meng-Tzu Weng, Liang-Chuan Lai, Jen-Hao Hsiao, Eric Y. Chuang, Chia-Tung Shun, Deng-Cheng Wu, Ai-Wen Kao, Chiao-Shung Chuang, Yen-Hsuan Ni, Ming-Jium Shieh, Chien-Chih Tung, [ ... ], Jau-Min Wong. SLCO3A1, A novel crohn's disease-associated gene, regulates nf-κB activity and associates with intestinal perforation. PLoS One,2014,9(6), e100515 (SCI)
  67. Ying-Hsia Shih, Xi-Zhang Lin, Chung-Hsin Yeh, Cheng-Liang Peng, Ming-Jium Shieh, Wuu-Jyh Lin, Tsai-Yueh Luo Preparation and therapeutic evaluation of (188)Re-thermogelling emulsion in rat model of hepatocellular carcinoma. International Journal of Nanomedicine, 2014.9(1).4191-4201 (SCI)
  68. Jyh-Chin Yang, Chun-Jung Lin, Hong-Long Wang, Jin-De Chen, John Y. Kao, Chia-Tung Shun, Chien-Wei Lu, Bor-Ru Lin, Ming-Jium Shieh, Ming-Chu Chang, Yu-Ting Chang, Shu-Chen Wei, Lin-Chih Lin, Wen-Chun Yeh, Jen-Shin Kuo, Chien-Chih Tung, Yew-Loong Leon, Teh-Hong Wang, Jau-Min Wong High-dose Dual Therapy Is Superior to Standard First-line or Rescue Therapy for Helicobacter pylori Infection. Clinical Gastroenterology and Hepatology2014, S1542-3565(14)01619-X (SCI)
  69. Yuan-I Chen, Cheng-Liang Peng, Pei-Chi Lee, Ming-Hsien Tsai, Chun-Yen Lin, Ying-Hsia Shih, Min-Feng Wei, Tsai-Yueh Luo and Ming-Jium Shieh Traceable Self-Assembly of Laser-Triggered Cyanine-Based Micelle for Synergistic Therapeutic Effect. Advanced healthcare materials, 2015 Jan (SCI)
  70. Meng-Tzu Weng, Shu-Chen Wei, Chun-Che Lin, Yuk-Min Tsang, Chia-Tung Shun, Jann-Yuan Wang, Ming-Jium Shieh, Cheng-Yi Wang, Jau-Min Wong Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection.Intestinal research ,2015;13(1):6-10
  71. Lin WC, Wong JM, Tung CC, Lin CP, Chou JW, Wang HY, Shieh MJ, Chang CH, Liu HH, Wei SC, Taiwan Society of Inflammatory Bowel Disease Multicenter Study. Fecal calprotectin correlated with endoscopic remission for Asian inflammatory bowel disease patients. World J Gastroenterol 2015; 21(48): 13566-13573.
  72. Tsai M-H, Peng C-L, Yao C-J, Shieh M-J. Enhanced efficacy of chemotherapeutic drugs against colorectal cancer using ligand-decorated self-breakable agents. RSC Adv 2015;5:92361–70.
  73. Chen K-C, Hsieh Y-S, Tseng Y-F, Shieh M-J, Chen J-S, Lai H-S, et al. Pleural Photodynamic Therapy and Surgery in Lung Cancer and Thymoma Patients with Pleural Spread. PLoS One 2015;10:e0133230.
  74. Shih Y-H, Peng C-L, Chiang P-F, Lin W-J, Luo T-Y, Shieh M-J. Therapeutic and scintigraphic applications of polymeric micelles: combination of chemotherapy and radiotherapy in hepatocellular carcinoma. Int J Nanomedicine 2015;10:7443–54.
  75. Lee P-C, Peng C-L, Shieh M-J. Combining the single-walled carbon nanotubes with low voltage electrical stimulation to improve accumulation of nanomedicines in tumor for effective cancer therapy. J Control Release 2016;225:140–51.
  76. Lee S-Y, Yang C-Y, Peng C-L, Wei M-F, Chen K-C, Yao C-J, Shieh M-J. A theranostic micelleplex co-delivering SN-38 and VEGF siRNA for colorectal cancer therapy. Biomaterials 2016;86:92–105.
  77. Chen Jenny L-Y, Chen J-P, Huang Y-S, Tsai Y-C, Tsai M-H, Jaw F-S, Cheng C-H, Kuo S-H, Shieh M-J. Radiosensitization in esophageal squamous cell carcinoma. Strahlentherapie Und Onkol 2016:1–9.

B. 研討會論文(Conference Paper)(2000年迄今)

  1. A targeting self-breakable agent for increased efficacy of chemotherapeutic drugs against Caco2 cells. BIODEVICES 2016 (9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC). 2016, February. Rome, Italy.
  2. Shin-Yu Lee, Ming-Jium Shieh. Gold Nanoshells With Micellar Core for The Delivery of Hydrophobic Chemotherapeutic and Cancer Photothermal Therapy. TechConnect World Innovation Conference & Expo - Nanotech 2016 Conference & Expo. 2016, May. Washington, D.C., USA.
  3. Development of Antibody as Carrier Incorporating Platinum-Based Agent for Targeted Therapy of Colorectal Cancer. Drug Delivery & Therapy World Congress 2016. 2016, August. Boston, MA, USA.
  4. Primary Study of the Stomach Sound Recording System, 2001, Dec., 台北, 中華民國生物醫學工程學會年會
  5. In Vitro Release of 5-ASA with pH-sensitive polymeric membrane, 2001, Feb., 台北, 中日生醫材料及藥物制放研討會
  6. Assistant Equipment of Electrogastrogram Research — Primary Study of the Gastric Sound System, 2002, Dec., 高雄, 中華民國生物醫學工程學會年會
  7. Colon-Specific 5-FU Release by pH-Sensitive Polymer and Detection by Microdialysis-HPLC System, 2002, Dec., 台北, 世界華人生物醫學工程研討會
  8. 大腸藥物釋放之臨床應用 , 2003, Mar., 台北, 生醫材料及藥物制放研討會
  9. 高分子奈米粒子做為藥物及基因載體的評估, 2004, 台北, 奈米國家型計畫奈米生醫研討會
  10. Studies on the subcellular trafficking of PAMAM dendrimer, 2005, May, Anaheim, California, U.S.A., Nanotechnology Conference and Trade Show
  11. A comparative study of photochemical internalization with different PAMAM dendrimer conjugates, 2005, June, Munich, Germany, 10th World Congress of The International Photodynamic Association
  12. Syntesis, photophysical properties, and in vitro evaluation of Meso-substituted porphyrins and chlorin photosensitizers for photodynamic therapy via mitochondia targeting, 2005, June, Munich, Germany, 10th World Congress of The International Photodynamic Association
  13. Shell cross-linked nanoparticle based on poly( -caprolactone)-poly(ethylene glycol) for photosensitizer delivery, 2006, May, Boston, Massachusetts, U.S.A.,NSTI Nanotechnology Conference and Trade Show
  14. Synthesis and photodynamic efficacy of PAMAM-photosensitiser conjugates,2006, May, Boston, Massachusetts, U.S.A., NSTI Nanotechnology Conference and Trade Show
  15. A novel nanocarrier for the photosenstizers and chemotherapeutic drugs delivery for the combined treatments of photodynamic therapy and chemotherapy, 2006,Dec, Tokyo, Japan, NANOBIO-TOKYO 2006
  16. Branched star porphyrin-polylactide composed nanoparticle for chemo-photodynamic therapies, 2007, Dec, Taipei, Taiwan, International Conference on Bionano Science
  17. An novel cisplatin-dendrimer phthalocyanine conjugate for cancer therapy, 2007, Dec, HsinChu, Taiwan, Annual Chinese Chemical Society & ICCT 2007 JointConference
  18. Anti-tumor effect and photosensitivity of micellar photosensitizer in colorectal cancer, 2008, Jan, NanTou, Taiwan, The 6th cross-strait workshop on nano science and technology
  19. Enhanced cytotoxicity of doxorubicin by micellar denderimer-based phthalocyanine-mediated photochemical internalization in drug-resistant MCF-7Cells, 2008, Dec., Singapore, 13th International Conference on BiomedicalEngineering
  20. Enhanced cytotoxicity of doxorubicin by micellar denderimer-based phthalocyanine-mediated photochemical internalization in drug-resistant MCF-7 cells, 2008, Dec., Singapore, 13th International Conference on Biomedicall Engineering
  21. Enhancement of Protoprophyrin IX Accumulation by Alginate-Incorporated and Folic Acid-Conjugated Chitosan Nano-particles for Colorectal Cancer Photodynamic Detection, 2009, Nov., Tsukuba-shi, Japan, 20th Asia Pacific CancerConference
  22. Cell Death of Colorectal Cancer Stem-like Cell was Induced by Photodynami c Therapy with Protoporphyrin Ⅸ, 2009, Nov., Tsukuba-shi, Japan, 20th Asia Pacific Cancer Conference
  23. Enhanced Cell Electro-permeabilisation Combined with Phototherapy to Target-Killing Cancer Cells by Using Multi Functional Carbon Nanotubes, 2011, Boston, Massachusetts, U.S.A., NSTI Nanotechnology Conference and Trade Show
  24. A Novel Multifunctional Nanomedicine for Magnetic Resonance Imaging and Treatment of Cancer,2013,Nov., Osaka, Japan, ICEAS The 3rd International Conference on Engineering and Applied Science.
  25. Novel Photo-Thermal Controlled Drug-releasing Vector for Cancer Detection and Treatment ,2013,May,Washington D.C.,USA,16th Nanotech conference

C. 專書及專書論文(Books and Chapter in Book)

  1. 高危險性醫療儀器之安全作業(ISBN 957-99939-0-4): 第四章(內視鏡之感染與清潔消毒)
  2. 醫用超音波專輯(ISBN 957-99939-2-0): 超音波在消化器病之應用
  3. 醫學工程原理與應用(ISBN 957-09-1045-3): 第十三章 (應用內視鏡學)

D. 技術報告及其他等(Technological Report and Others)

E. 專利(Patents)

  1. CHEN CHUNG NUN, SHIEH MING JIUM, LAI CHIEN HSUN, LAI PING SHAN,Method for forming positively charged polymeric micelle, Taiwan Patent I271197,2007/01/00~2025/10/00