國立台灣大學 醫學工程學研究所

教師研究成果

楊台鴻 Tai-Horng Young

A. 期刊論文(Journal Paper) (*: corresponding author)

  1. CH Yang, YW Pan, JJ Guo, TH Young, WY Chiu, KH Hsieh, Synthesis and application of polyurethane basic organic-inorganic hybrid materials as highly hydrophobic coatings, J. Polym. Res., accepted.
  2. NC Cheng, TY Hsieh, TH Young*, High glucose-induced reactive oxygen species generation promotes stemness in human adipose-derived stem cells, Cytotherapy, accepted.
  3. HC Tsai, YC Li, TH Young, MH Chen,Inhibition of oral and cervical cancer cell growth and migration by citrus polyphenol, J. Formos. Med. Assoc., accepted.
  4. HC Tsai, YC Li, TH Young, MH Chen, Novel micro-injector for carrying bone substitutes for bone regeneration in periodontal diseases, J. Formos. Med. Assoc., accepted.
  5. HC Tsai, YC Li, TH Young, MH Chen, Citrus polyphenol for oral wound healing in oral ulcers and periodontal diseases, J. Formos. Med. Assoc., accepted.
  6. YS Chou, YC Lin, TH Young*, PJ Lou, Effects of fibroblasts on the function of acinar cells from the same human parotid gland, Head Neck-J. Sci. Spec., accepted.
  7. YC Li, LK Tsai, TH Young*, Intraventricular infusion of a low fraction of serum enhances neurogenesis and improves recovery in a rodent stroke model, Neurosci Lett., 611 (2016) 14-20.
  8. YC Li, MW Lin, MH Yen, MY Fan, JT Wu, TH Young, JY Cheng, SJ Lin, Programmable laser-assisted surface microf TH abrication on a polyvinyl alcohol-coated glass chip with self-changing cell adhesivity for heterotypic cell patterning, ACS Appl. Mater. Inter., 7 (2015) 22322-22332.
  9. CW Tsai, YT Kao, IN Chiang, JH Wang, TH Young*, Chitosan treatment delays the induction of senescence in human foreskin fibroblast strains, PLoS One, 10 (2015), e0140747.
  10. YS Chou, JN Lu, YC Li, JH Wang, TH Young*, The surface potential variation of neural stem/progenitor cells during differentiation process. Journal of Neurology & Neuroscience, 6 (2015) No. 3:38.
  11. YJ Chen, CCJ Yao, CH Huang, HH Chang, TH Young*, Hexosamine-induced TGF-ß signaling and osteogenic differentiation of dental pulp stem cells is dependent on N-acetylglucosaminyltransferase V (GnT-V), BioMed Res. Int., (2015) 924397, 11 pages.
  12. YS Chou, TH Young*, PJ Lou, Effects of biomaterial-derived fibroblast conditioned medium on the a-amylase expression of parotid gland acinar cells, Acta Biomater., 27 (2015) 214–223.
  13. YC Li, JH Wang, LK Tsai, TL Yang, YA Chen, TC Chang, PJ Lou, TH Young*, 3,6-Bis(1-methyl-4-vinylpyridinium)-carbazole diiodide as a marker for tracking living neural stem/ precursor cells, J. Mat. Chem. B, 3 (2015) 2067-2074
  14. CH Yang, SH Chen, YW Pan, CN Chuang, WC Chao, TH Young, WY Chiu, CK Wang, KH Hsieh, Preparation and characterization of methoxy-poly (ethylene glycol) side chain grafted onto chitosan as a wound dressing film, J. Appl. Polym. Sci., 132 (2015) 42340.
  15. TW Huang, TH Young*, Novel porous oral patches for mild obstructive sleep apnea patients with mouth-breathing: A pilot study, Otolaryngol. Head Neck Surg., 152 (2015) 369-373.
  16. YC Li, LK Tsai, TL Yang, YA Chen, TC Chang, PJ Lou, TH Young*, A novel bio-marker for tracking viable neural stem/precursor cells, J. Mat. Chem. B, 3 (2015) 2067-2074.
  17. IC Lee, TL Lo, TH Young, YC Li, NG Chen, CH Chen, YC Chang, Differentiation of neural stem/progenitor cells using low-intensity ultrasound, Ultrasound Med. Biol. 40 (2014) 2195-2206.
  18. YH Chen, SH Chang, IJ Wang, TH Young*, The mechanism for keratinocyte detaching from pH-responsive chitosan, Biomaterials, 35 (2014) 9247-9254.
  19. YC Lin, PJ Lou, TH Young*, Chitosan as an adjuvant-like substrate for dendritic cell culture to enhance antitumor effects, Biomaterials, 35 (2014) 8867-8875.
  20. TH Young, IJ Wang, FR Hu, TJ Wang, Fabrication of a bioengineered corneal endothelial cell sheet using chitosan/polycaprolactone blend membranes, Colloid Surface B, 116 (2014) 403-410.
  21. CH Wang, RW Chang, YH Ko, PR Tsai, SS Wang, YS Chen, WJ Ko, CY Chang, TH Young, KC Chang, Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde, PLoS One, 9 (2014) e90471
  22. YC Li, LK Tsai, JH Wang, TH Young*, A neural stem/precursor cell monolayer for neural tissue engineering, Biomaterials, 35 (2014) 1192-1204.
  23. TL Yang, L Lin, PJ Lou, TC Chang, TH Young*, Detection of cell carcinogenic transformation by a quadruplex DNA binding fluorescent probe, PLoS One, 9 (2014) e86143.
  24. CH Chen, TH Young, CH Huang, HH Chang, CL Chen, HF Chien, JS Chen, HS Lai, NC Cheng, Patient-centered wound teleconsultation for cutaneous wounds: a feasibility study, Ann. Plast. Surg., 72 (2014) 220-224.
  25. CH Hung, YC Li, TH Young*, Induction of neuronal differentiation of embryonic rat cortical neurospheres by nerve growth factor and fetal bovine serum on the nonadherent and adherent substrates, Biomed. Eng.-Appl. Basis Commun., 25 (2013) 1250053.
  26. HY Tan, W Lo, CM Hsueh, CY Wang, SJ Lin, CY Dong, TH Young*, Characterizing three-dimensional microstructure of collagen/chitosan scaffolds using multiphoton microscope, Biomed. Eng.-Appl. Basis Commun., 25 (2013) 1350038.
  27. SH Chang, IN Chiang, YH Chen, TH Young*, Serum-free culture of rat proximal tubule cells with enhanced function on chitosan, Acta Biomater., 9 (2013) 8941-8951.
  28. TW Huang, YH Chan, HW Su, YS Chou, TH Young*, Increased mucociliary differentiation and aquaporins formation of respiratory epithelial cells on retinoic acid-loaded hyaluronan derivative membranes, Acta Biomater., 9 (2013) 6783-6789.
  29. HH Lee, CC Chang, MJ Shieh, JP Wang, YT Chen, TH Young*, SC Hung, Hypoxia enhances chondrogenesis and prevents terminal differentiation through PI3K/Akt/FoxO dependent anti-apoptotic effect, Sci. Rep., 3 (2013) 2683.
  30. NC Cheng, SY Chen, JR Li, TH Young*, Short-term spheroid formation enhances the regenerative capacity of adipose-derived stem cells by promoting stemness, angiogenesis and chemotaxis, Stem Cells Transl. Med., 2 (2013) 584-594.
  31. CC Lin, CC Wang, KC Hung, CL Chen, CC Yong, TH Young, E Kobayash, Study of porcine hepatocyte-entrapped bioartificial liver in surgery-induced fulminant hepatic failure rabbits, Biochem. Eng. J., 76 (2013) 55-59.
  32. CH Wang, TM Wang, TH Young, YK Lai, ML Yen, The critical role of ECM proteins within the human MSC niche in endothelial differentiation, Biomaterials, 34 (2013) 4223-4234.
  33. HY Tan, YL Chang, W Lo, CM Hsueh, WL Chen, AA Ghazaryan, PS Hu, TH Young, SJ Chen, CY Dong, Characterizing the morphological changes of collagen-crosslinking treated corneas by Fourier transform-second harmonic generation imaging, J. Cataract. Refr. Surg., 39 (2013) 779-788.
  34. NC Cheng, BT Estes, TH Young, F Guilak, Genipin-crosslinked cartilage-derived matrix as a scaffold for human adipose-derived stem cell chondrogenesis, Tissue Eng., 19 (2013) 484-496.
  35. YC Li, YT Liao, HH Chang, TH Young*, Covalent bonding of GYIGSR to EVAL membrane surface to improve migration and adhesion of cultured neural stem/precursor cells, Colloid Surface B, 102 (2013) 53-62.
  36. YC Li, CR Chen, TH Young*, Pearl extract enhances the migratory ability of fibroblasts in a wound healing model, Pharm. Biol., 51 (2013) 289-297.
  37. YS Chou, CC Chang, TC Chang, TL Yang, TH Young*, PJ Lou, Photo-induced antitumor effect of 3,6-bis(1-methyl-4-vinylpyridinium) carbazole diiodide (BMVC), BioMed Research International (J. Biomed. Biotechnol.), Volume 2013, Article ID 930281, 10 pages.
  38. YH Chen, SH Chang, TJ Wang, IJ Wang, TH Young*, Cell fractionation on pH-responsive chitosan surface, Biomaterials, 34 (2013) 854-863.
  39. TL Yang, L Lin, YC Hsaio, HW Lee, TH Young*, Chitosan biomaterials induce branching morphogenesis in a model of tissue-engineered glandular organs in serum-free conditions, Tissue Eng., 18 (2012) 2220-2230.
  40. HJ Shao, CC Ho, YT Lee, CS Chen, JH Wang, TH Young*, Chondrogenesis of human bone marrow mesenchymal cells by transforming growth factors ß1 through cell shape changes on controlled biomaterials, J. Biomed. Mater. Res. A, 100A (2012) 3344-3352.
  41. NC Cheng, HH Chang, YK Tu, TH Young*, Efficient transfer of human adipose-derived stem cells by chitosan/gelatin blend films, J. Biomed. Mater. Res. B, 100B (2012) 1369-1377.
  42. YC Li, YC Lin, TH Young*, Combination of media, biomaterials and extra cellular matrix proteins to enhance the differentiation of neural stem/precursor cells into neurons, Acta Biomater., 8 (2012) 3035-3048.
  43. TJ Wang, IJ Wang, JN Lu, TH Young*, Novel chitosan-polycaprolactone blends as potential scaffold and carrier for corneal endothelial transplantation, Mol. Vis., 18 (2012) 255-264.
  44. TJ Wang, IJ Wang, YH Chen, TH Young*, Polyvinylidene fluoride for proliferation and preservation of bovine corneal endothelial cells by enhancing type IV collagen production and deposition, J. Biomed. Mater. Res., 100A (2012) 252-260.
  45. BY Yu, PY Chen, YM Sun, YT Lee, TH Young, Response of human mesenchymal stem cells (hMSCs) to the topographic variation of poly(3-Hydroxybutyrate-co-3-Hydroxyhexanoate) (PHBHHx) films, J. Biomat. Sci-Polym. E., 23 (2012) 1-26.
  46. TJ Wang, IJ Wang, S Chen, YH Chen, TH Young*, The phenotypic response of bovine corneal endothelial cells on chitosan/polycaprolactone blends, Colloid Surface B, 90 (2012) 236-243.
  47. NC Cheng, S Wang, TH Young*, The influence of spheroid formation of human adipose-derived stem cells on chitosan films on stemness and differentiation capabilities, Biomaterials, 33 (2012) 1748-1758.
  48. YH Chen, YC Chung, IJ Wang, TH Young*, Control of cell attachment on pH-responsive chitosan surface by precise adjustment of medium pH, Biomaterials, 33 (2012) 1336-1342.
  49. PC Tseng, TH Young, TM Wang, HW Peng, SM Hou, ML Yen, Spontaneous osteogenesis of MSCs cultured on 3D microcarriers through alteration of cytoskeletal tension, Biomaterials 33 (2012) 556-564.
  50. YJ Chen, MC Chung, CC Yao, CH Huang, HH Chang, JH Jeng, TH Young*, The effect of acellular amniotic membrane matrix on osteogenic differentiation and ERK1/2 signaling in human dental apical papilla cells, Biomaterials 33 (2012) 455-463.
  51. YH Chan, TW Huang, YS Chou, SH Hsu, WF Su, PJ Lou, TH Young*, Formation of post-confluence structure in human parotid gland acinar cells on PLGA through regulation of E-cadherin, Biomaterials 33 (2012) 464-472.
  52. Tsao, C.T., C.H. Chang, Y.Y. Lin, M.F. Wu, J.L. Wang, T.H. Young, J.L. Han, and K.H. Hsieh, Evaluation of chitosan/gamma-poly(glutamic acid) polyelectrolyte complex for wound dressing materials. Carbohydrate Polymers. 84(2): p. 812-819.(2011) (SCI)
  53. Lu, J.N., C.C. Wang, and T.H. Young*, The Behaviors of Long-Term Cryopreserved Human Hepatocytes on Different Biomaterials. Artificial Organs. 35(3): p. E65-E72.(2011) (SCI)
  54. Lee, Y.T., B.Y. Yu, H.J. Shao, C.H. Chang, Y.M. Sun, H.C. Liu, S.M. Hou, and T.H. Young, Effects of the Surface Characteristics of Nano-Crystalline and Micro-Particle Calcium Phosphate/Chitosan Composite Films on the Behavior of Human Mesenchymal Stem Cells In Vitro. Journal of Biomaterials Science-Polymer Edition. 22(17): p. 2369-2388.(2011) (SCI)
  55. Ke, J.H., M.F. Wei, M.J. Shieh, and T.H. Young*, Imidazole/Poly(Ethylene Glycol)-Substituted Poly(N-(8-Aminooctyl)Acrylamide) as Biocompatible and Efficient Gene Carrier. Journal of Biomaterials Science-Polymer Edition. 22(13): p. 1753-1775.(2011) (SCI)
  56. Ke, J.H., M.F. Wei, M.J. Shieh, and T.H. Young*, Design, Synthesis and Evaluation of Cationic Poly(N-substituent acrylamide)s for In Vitro Gene Delivery. Journal of Biomaterials Science-Polymer Edition. 22(9): p. 1215-1236.(2011) (SCI)
  57. Huang, C.W., H.Y. Chen, M.H. Yen, J.J.W. Chen, T.H. Young, and J.Y. Cheng, Gene Expression of Human Lung Cancer Cell Line CL1-5 in Response to a Direct Current Electric Field. PLoS One. 6(10).(2011) (SCI)
  58. Hsieh, C.H., Y.A. Ku, L.H. Chiu, T.H. Young, and Y.Y. Huang, A Transdermal Drug Delivery System Containing Deferioxamine Mesylate for the Treatment of Beta-Thalassaemia Major. Biomedical Engineering-Applications Basis Communications. 23(1): p. 29-35.(2011) (SCI)
  59. Hsiao, Y.C., H.W. Lee, Y.T. Chen, T.H. Young, and T.L. Yang, The impact of compositional topography of amniotic membrane scaffold on tissue morphogenesis of salivary gland. Biomaterials. 32(19): p. 4424-4432.(2011) (SCI)
  60. Chung, Y.C., M.F. Wei, F.H. Chang, and T.H. Young*, PEGylated Guanidinylated Polyallylamine as Gene-Delivery Carrier. Journal of Biomaterials Science-Polymer Edition. 22(14): p. 1829-1843.(2011) (SCI)
  61. Chung, Y.C., T.Y. Cheng, and T.H. Young*, The role of adenosine receptor and caveolae-mediated endocytosis in oligonucleotide-mediated gene transfer. Biomaterials. 32(19): p. 4471-4480.(2011) (SCI)
  62. Cheng, N.C., B.T. Estes, T.H. Young, and F. Guilak, Engineered cartilage using primary chondrocytes cultured in a porous cartilage-derived matrix. Regenerative Medicine. 6(1): p. 81-93.(2011) (SCI)
  63. Chan, Y.H., T.W. Huang, T.H. Young*, and P.J. Lou, Selective Culture of Different Types of Human Parotid Gland Cells. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck. 33(3): p. 407-414.(2011) (SCI)
  64. Chan, Y.H., T.W. Huang, T.H. Young*, and P.J. Lou, Human Salivary Gland Acinar Cells Spontaneously Form Three-Dimensional Structures and Change the Protein Expression Patterns. Journal of Cellular Physiology. 226(11): p. 3076-3085.(2011) (SCI)
  65. Yu, B.Y., P.Y. Chen, Y.M. Sun, Y.T. Lee, and T.H. Young, Effects of the Surface Characteristics of Polyhydroxyalkanoates on the Metabolic Activities and Morphology of Human Mesenchymal Stem Cells. Journal of Biomaterials Science-Polymer Edition. 21(1): p. 17-36.(2010) (SCI)
  66. Young, T.H., H.H. Chang, D.J. Lin, and L.P. Cheng, Surface modification of microporous PVDF membranes for neuron culture. Journal of Membrane Science. 350(1-2): p. 32-41.(2010) (SCI)
  67. Yen, M.H., C.W. Huang, W.C. Hsu, T.H. Young, K. Zimmer, and J.Y. Cheng, Crack-free micromachining on glass substrates by visible LIBWE using liquid metallic absorbers. Applied Surface Science. 257(1): p. 87-92.(2010) (SCI)
  68. Yang, T.L., Y.C. Hsiao, S.J. Lin, H.W. Lee, P.J. Lou, J.Y. Ko, and T.H. Young, Biomaterial mediated epithelial-mesenchymal interaction of salivary tissue under serum free condition. Biomaterials. 31(2): p. 288-295.(2010) (SCI)
  69. Yang, S.J., J.W. Chen, F.H. Lin, T.H. Young, P.J. Lou, and M.J. Shieh, Colorectal Cancer Cell Detection by Folic Acid-Conjugated Chitosan Nanoparticles. Biomedical Engineering-Applications Basis Communications. 22(1): p. 9-17.(2010) (SCI)
  70. Wang, J.H., U.H. Lin, C.H. Lin, Y.C. Chung, C.R. Chen, Y.C. Kao, J.Y. Lai, and T.H. Young*, Change in neuron aggregation and neurite fasciculation on EVAL membranes modified with different diamines. Journal of Biomedical Materials Research Part A. 94A(2): p. 489-498.(2010) (SCI)
  71. Wang, I.J., M.C. Jhuang, Y.H. Chen, L.K. Yeh, C.Y. Liu, and T.H. Young, Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells. PLoS One. 5(8).(2010) (SCI)
  72. Tsai, W.C., C.J. Liao, C.T. Wu, C.Y. Liu, S.C. Lin, T.H. Young, S.S. Wu, and H.C. Liu, Clinical result of sintered bovine hydroxyapatite bone substitute: analysis of the interface reaction between tissue and bone substitute. Journal of Orthopaedic Science. 15(2): p. 223-232.(2010) (SCI)
  73. Shao, H.J., Y.T. Lee, C.S. Chen, J.H. Wang, and T.H. Young, Modulation of gene expression and collagen production of anterior cruciate ligament cells through cell shape changes on polycaprolactone/chitosan blends. Biomaterials. 31(17): p. 4695-4705.(2010) (SCI)
  74. Shao, H.J., C.S. Chen, Y.T. Lee, J.H. Wang, and T.H. Young, The phenotypic responses of human anterior cruciate ligament cells cultured on poly(epsilon-caprolactone) and chitosan. Journal of Biomedical Materials Research Part A. 93A(4): p. 1297-1305.(2010) (SCI)
  75. Lou, P.J., M.Y. Chiu, C.C. Chou, B.W. Liao, and T.H. Young*, The effect of poly (ethylene-co-vinyl alcohol) on senescence-associated alterations of human dermal fibroblasts. Biomaterials. 31(7): p. 1568-1577.(2010) (SCI)
  76. Lee, Y.T., H.J. Shao, J.H. Wang, H.C. Liu, S.M. Hou, and T.H. Young*, Hyaluronic Acid Modulates Gene Expression of Connective Tissue Growth Factor (CTGF), Transforming Growth Factor-beta 1 (TGF-beta 1), and Vascular Endothelial Growth Factor (VEGF) in Human Fibroblast-Like Synovial Cells from Advanced-Stage Osteoarthritis In Vitro. Journal of Orthopaedic Research. 28(4): p. 492-496.(2010) (SCI)
  77. Ke, J.H. and T.H. Young*, Multilayered polyplexes with the endosomal buffering polycation in the core and the cell uptake-favorable polycation in the outer layer for enhanced gene delivery. Biomaterials. 31(35): p. 9366-9372.(2010) (SCI)
  78. Huang, T.W., P.W. Cheng, Y.H. Chan, T.H. Yeh, Y.H. Young*, and T.H. Young, Regulation of ciliary differentiation of human respiratory epithelial cells by the receptor for hyaluronan-mediated motility on hyaluronan-based biomaterials. Biomaterials. 31(26): p. 6701-6709.(2010) (SCI)
  79. Huang, T.W., P.W. Cheng, Y.H. Chan, C.T. Wang, K.M. Fang, and T.H. Young*, Clinical and biomechanical analyses to select a suture material for uvulopalatopharyngeal surgery. Otolaryngology-Head and Neck Surgery. 143(5): p. 655-661.(2010) (SCI)
  80. Huang, T.W., Y.H. Chan, P.W. Cheng, Y.H. Young*, P.J. Lou, and T.H. Young, Increased mucociliary differentiation of human respiratory epithelial cells on hyaluronan-derivative membranes. Acta Biomaterialia. 6(3): p. 1191-1199.(2010) (SCI)
  81. Huang, C.H., W.Y. Tseng, C.C. Yao, J.H. Jeng, T.H. Young*, and Y.J. Chen, Glucosamine Promotes Osteogenic Differentiation of Dental Pulp Stem Cells through Modulating the Level of the Transforming Growth Factor-beta Type I Receptor. Journal of Cellular Physiology. 225(1): p. 140-151.(2010) (SCI)
  82. Chung, Y.C., W.Y. Hsieh, and T.H. Young*, Polycation/DNA complexes coated with oligonucleotides for gene delivery. Biomaterials. 31(14): p. 4194-4203.(2010) (SCI)
  83. Chung, Y.C., F.H. Chang, M.F. Wei, and T.H. Young, A variable gene delivery carrier-biotinylated chitosan/polyethyleneimine. Biomedical Materials. 5(6).(2010) (SCI)
  84. Chang, C.H., C.T. Tsao, K.Y. Chang, J.L. Wang, T.H. Young, J.L. Han, and K.H. Hsieh, Chitosan Membrane with Surface-bonded Growth Factor in Guided Tissue Regeneration Applications. Journal of Bioactive and Compatible Polymers. 25(5): p. 465-482.(2010) (SCI)
  85. Yu, B.Y., S.W. Hu, Y.M. Sun, Y.T. Lee, and T.H. Young, Modulating the Activities of Human Mesenchymal Stem Cells (hMSCs) and C3A/HepG2 Hepatoma Cells by Modifying the Surface Characteristics of Poly(3-hydroxybutyrate-co-3-hydroxyhexnoate) (PHBHHx). Journal of Biomaterials Science-Polymer Edition. 20(9): p. 1275-1293.(2009) (SCI)
  86. Yu, B.Y., C.R. Chen, Y.M. Sun, and T.H. Young, The response of rat cerebellar granule neurons (rCGNs) to various polyhydroxyalkanoate (PHA) films. Desalination. 245(1-3): p. 639-646.(2009) (SCI)
  87. Young, T.H., H.R. Tu, C.C. Chan, Y.C. Huang, M.H. Yen, N.C. Cheng, H.C. Chiu, and S.J. Lin, The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell-substratum adhesivity and cell motility. Biomaterials. 30(28): p. 5031-5040.(2009) (SCI)
  88. Young, T.H., U.H. Lin, D.J. Lin, H.H. Chang, and L.P. Cheng, Immobilization of L-Lysine on Microporous PVDF Membranes for Neuron Culture. Journal of Biomaterials Science-Polymer Edition. 20(5-6): p. 703-720.(2009) (SCI)
  89. Yeh, L.K., Y.H. Chen, C.S. Chiu, F.R. Hu, T.H. Young, and I.J. Wang, The phenotype of bovine corneal epithelial cells on chitosan membrane. Journal of Biomedical Materials Research Part A. 90A(1): p. 18-26.(2009) (SCI)
  90. Yang, T.L. and T.H. Young*, The specificity of chitosan in promoting branching morphogenesis of progenitor salivary tissue. Biochemical and Biophysical Research Communications. 381(4): p. 466-470.(2009) (SCI)
  91. Yang, T.L. and T.H. Young*, Chitosan cooperates with mesenchyme-derived factors inregulating salivary gland epithelial morphogenesis. Journal of Cellular and Molecular Medicine. 13(9A): p. 2853-2863.(2009) (SCI)
  92. Yang, S.J., M.J. Shieh, F.H. Lin, P.J. Lou, C.L. Peng, M.F. Wei, C.J. Yao, P.S. Lai, andT.H. Young, Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles. Cancer Letters. 273(2): p. 210-220.(2009) (SCI)
  93. Shao, H.J., C.S. Chen, I.C. Lee, J.H. Wang, and T.H. Young, Designing a Three-dimensional Expanded Polytetrafluoroethylene-Poly(lactic-co-glycolic acid) Scaffold for Tissue Engineering. Artificial Organs. 33(4): p. 309-317.(2009) (SCI)
  94. Lou, P.J., W.F. Cheng, Y.C. Chung, C.Y. Cheng, L.H. Chiu, and T.H. Young*, PMMA particle-mediated DNA vaccine for cervical cancer. Journal of Biomedical Materials Research Part A. 88A(4): p. 849-857.(2009) (SCI)
  95. Lin, D.J., D.T. Lin, T.H. Young, T.C. Chen, H.H. Chang, and L.P. Cheng, Immobilization of DNA on Microporous PVDF Membranes by Plasma Polymerization. Journal of Biomaterials Science-Polymer Edition. 20(13): p. 1943-1959.(2009) (SCI)
  96. Lee, I.C., Y.T. Lee, B.Y. Yu, J.Y. Lai, and T.H. Young*, The behavior of mesenchymal Stem cells on micropatterned PLLA membranes. Journal of Biomedical Materials Research Part A. 91A(3): p. 929-938.(2009) (SCI)
  97. Huang, T.W., Y.H. Young, P.W. Cheng, Y.H. Chan, and T.H. Young*, Culture of Nasal Epithelial Cells Using Chitosan-Based Membranes. Laryngoscope. 119(10): p. 2066-2070.(2009) (SCI)
  98. Huang, C.W., J.Y. Cheng, M.H. Yen, and T.H. Young, Electrotaxis of lung cancer cells in a multiple-electric-field chip. Biosensors & Bioelectronics. 24(12): p. 3510-3516.(2009) (SCI)
  99. Huang, C.H., M.H. Chen, T.H. Young, J.H. Jeng, and Y.J. Chen, Interactive Effects of Mechanical Stretching and Extracellular Matrix Proteins on Initiating Osteogenic Differentiation of Human Mesenchymal Stem Cells. Journal of Cellular Biochemistry. 108(6): p. 1263-1273.(2009) (SCI)
  100. Chen, Y.H., I.J. Wang, and T.H. Young, Formation of Keratocyte Spheroids on Chitosan-Coated Surface Can Maintain Keratocyte Phenotypes. Tissue Engineering Part A. 15(8): p. 2001-2013.(2009) (SCI)
  101. Chen, R.S., Y.J. Chen, M.H. Chen, and T.H. Young, The behavior of rat tooth germ cells on poly(vinyl alcohol). Acta Biomaterialia. 5(4): p. 1064-1074.(2009) (SCI)
  102. Chen, R.S., M.H. Chen, and T.H. Young*, Induction of differentiation and mineralization in rat tooth germ cells on PVA through inhibition of ERK1/2. Biomaterials. 30(4): p. 541-547.(2009) (SCI)
  103. Chen, M.H., Y.J. Chen, C.C. Liao, Y.H. Chan, C.Y. Lin, R.S. Chen, and T.H. Young*, Formation of salivary acinar cell spheroids in vitro above a polyvinyl alcohol-coated surface. Journal of Biomedical Materials Research Part A. 90A(4): p. 1066-1072.(2009) (SCI)
  104. Chen, C.R., Y.C. Li, and T.H. Young*, Gallium nitride induces neuronal differentiation markers in neural stem/precursor cells derived from rat cerebral cortex. Acta Biomaterialia. 5(7): p. 2610-2617.(2009) (SCI)
  105. Yu, B.Y., P.Y. Chen, Y.M. Sun, Y.T. Lee, and T.H. Young, The behaviors of human mesenchymal stem cells on the (SCI)poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) membranes. Desalination. 234(1-3): p. 204-211.(2008) (SCI)
  106. Young, T.H., J.N. Lu, D.J. Lin, C.L. Chang, H.H. Chang, and L.P. Cheng, Immobilization of l-lysine on dense and porous poly(vinylidene fluoride) surfaces for neuron culture. Desalination. 234(1-3): p. 134-143.(2008) (SCI)
  107. Young, T.H., C.Y. Lee, H.C. Chiu, C.J. Hsu, and S.J. Lin, Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly(ethylene-co-vinyl alcohol) membranes for hair follicle regeneration. Biomaterials. 29(26): p. 3521-3530.(2008) (SCI)
  108. Yang, T.L. and T.H. Young*, The enhancement of submandibular gland branch formation on chitosan membranes. Biomaterials. 29(16): p. 2501-2508.(2008)
  109. Yang, T.L., Y.C. Hsiao, and T.H. Young*, Comparison of Plga, Pcl, and Chitosan in Salivary Gland Branching Morphogenesis. Biomedical Engineering-Applications Basis Communications. 20(5): p. 287-296.(2008) (SCI)
  110. Tseng, C.L., S.Y.H. Wu, W.H. Wang, C.L. Peng, F.H. Lin, C.C. Lin, T.H. Young, and M.J. Shieh, Targeting efficiency and biodistribution of biotinylated-EGF-conjugated gelatin nanoparticles administered via aerosol delivery in nude mice with lung cancer. Biomaterials. 29(20): p. 3014-3022.(2008) (SCI)
  111. Tan, H.Y., M.G. Lin, W.C. Hsiao, S.J. Lin, L.K. Wen, W.L. Chen, C.Y. Dong, and T.H. Young, Characterizing phase-separated microstructure of polymeric blended membrane using combined multiphoton and reflected confocal imaging. Optics Express. 16(6): p. 3818-3827.(2008) (SCI)
  112. Sun, Y., H.Y. Tan, S.J. Lin, H.S. Lee, T.Y. Lin, S.H. Jee, T.H. Young, W. Lo, W.L. Chen, and C.Y. Dong, Imaging tissue engineering scaffolds using multiphoton microscopy. Microscopy Research and Technique. 71(2): p. 140-145.(2008) (SCI)
  113. Cheng, J.Y., M.H. Yen, C.T. Kuo, and T.H. Young, A transparent cell-culture microchamber with a variably controlled concentration gradient generator and flow field rectifier. Biomicrofluidics. 2(2).(2008) (SCI)
  114. Chen, Y.J., C.H. Huang, I.C. Lee, Y.T. Lee, M.H. Chen, and T.H. Young*, Effects of cyclic mechanical stretching on the mRNA expression of tendon/ligament-related and osteoblast-specific genes in human mesenchymal stem cells. Connective Tissue Research. 49(1): p. 7-14.(2008) (SCI)
  115. Chen, R.S., Y.J. Chen, M.H. Chen, and T.H. Young, Cell-surface interactions of rat tooth germ cells on various biomaterials (vol 83, pg 241, 2007). Journal of Biomedical Materials Research Part A. 84A(2): p. 567-567.(2008) (SCI)
  116. Chen, C.R. and T.H. Young*, Neurons cultured on GaN and is associated with synapsin I and MAP2 expression. Biomedical Engineering-Applications Basis Communications. 20(2): p. 75-82.(2008) (SCI)
  117. Chen, C.R. and T.H. Young*, The effect of gallium nitride on long-term of neuritic function in cerebellar culture induced aging granule cells. Biomaterials. 29(11): p. 1573-1582.(2008) (SCI)
  118. Young, T.H.*, T.N. Shiau, and Z.H. Kuo, Dynamic stability of rotor-bearing systems subjected to random axial forces. Journal of Sound and Vibration. 305(3): p. 467-480.(2007) (SCI)
  119. Wang, T.W., H.C. Wu, W.R. Wang, F.H. Lin, P.J. Lou, M.J. Shieh, and T.H. Young, The development of magnetic degradable DP-Bioglass for hyperthermia cancer therapy. Journal of Biomedical Materials Research Part A. 83A(3): p. 828-837.(2007) (SCI)
  120. Wang, C.C., J.N. Lu, and T.H. Young*, The alteration of cell membrane charge after cultured on polymer membranes. Biomaterials. 28(4): p. 625-631.(2007) (SCI)
  121. Tseng, C.L., T.W. Wang, G.C. Dong, S.Y.H. Wu, T.H. Young, M.J. Shieh, P.J. Lou, and F.H. Lin, Development of gelatin nanoparticles with biotinylated EGF conjugation for lung cancer targeting. Biomaterials. 28(27): p. 3996-4005.(2007) (SCI)
  122. Lee, I.C., J.H. Wang, Y.T. Lee, and T.H. Young*, The differentiation of mesenchymal stem cells by mechanical stress or/and co-culture system. Biochemical and Biophysical Research Communications. 352(1): p. 147-152.(2007) (SCI)
  123. Lee, I.C., J.H. Wang, Y.T. Lee, and T.H. Young*, Development of a useful technique to discriminate anterior cruciate ligament cells and mesenchymal stem cells - The application of cell electrophoresis. Journal of Biomedical Materials Research Part A. 82A(1): p. 230-237.(2007) (SCI)
  124. Lai, P.S., P.J. Lou, C.L. Peng, C.L. Pai, W.N. Yen, M.Y. Huang, T.H. Young, and M.J. Shieh, Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy. Journal of Controlled Release. 122(1): p. 39-46.(2007) (SCI)
  125. Hung, K.C., C.C. Yong, Y.S. Chen, H.L. Eng, F.Y. Kuo, C.C. Lin, T.H. Young, E. Kobayashi, C.L. Chen, and C.C. Wang, A surgical model of fulminant hepatic failure in rabbits. Liver International. 27(10): p. 1333-1341.(2007) (SCI)
  126. Cheng, J.Y., M.H. Yen, W.C. Hsu, J.H. Jhang, and T.H. Young, ITO patterning by a low power Q-switched green laser and its use in the fabrication of a transparent flow meter. Journal of Micromechanics and Microengineering. 17(11): p. 2316-2323.(2007) (SCI)
  127. Chen, R.S., Y.J. Chen, M.H. Chen, and T.H. Young, Cell-surface interactions of rat tooth germ cells on various biomaterials. Journal of Biomedical Materials Research Part A. 83A(1): p. 241-248.(2007) (SCI)
  128. Chang, K.Y., L.W. Chen, T.H. Young, and K.H. Hsieh, PEI/EVAL blend membranes for granule neuronal cell culture. Journal of Polymer Research. 14(3): p. 229-243.(2007) (SCI)

B. 研討會論文(Conference Paper)

  1. TH Young, Polymer membrane changes surface charge properties of cell membrane, MACRO 2004- 40th IUPAC World Polymer Congress.
  2. TH Young, Covalent bonding of amino acids to EVAL and PVA membranes for culturing of neuron cells, The International Congress on Membranes and Membrane Processes, ICOM 2002.
  3. TH Young, Assessment of poly (vinyl alcohol) bioartificial pancreas in vivo, SOCIETY FOR BIOMATERIALS, 27th Annual Meeting, 2001.
  4. TH Young, 5-ASA permeability enhancement by a pH-Sensitive EVAL membrane, 2001 Prague Meetings on Macromolecules, 41th Microsymposium, Polymer Membranes.

C. 專書及專書論文(Books and chapter in Book)

  1. KH Hsieh and TH Young, Hydrogel Biomaterials, JC Salamone ed., Polymeric Materials Encyclopedia, (1996) 3087-3092.

D. 技術報告及其他(Technological transfer and others)


E. 專利(Patents)


專利類別 專利編號 專利名稱
發明專利 I484983 應用於呼吸上皮細胞之敷料
MEDICAL DRESSING FOR RESPIRATORY EPITHELIAL CELLS
發明專利 I491382 用於貼附身體之貼帶
TAPE FOR ATTACHING TO THE HUMAN BODY
發明專利 I515024 幾丁聚醣-生物可分解高分子混摻組合物及其用途
COMPOSITION OF BLENDED CHITOSAN-BIODEGRADABLE POLYMER AND USE THEREOF
發明專利 I519641 細胞篩選方法及其套組
METHOD FOR SORTING CELLS AND KITS THEREOF
發明專利 I403582 促使神經幹細胞增生及/或分化的培養基
MEDIUM FOR PROMOTING PROLIFERATION AND/OR DIFFERENTIATION OF NEURAL STEM CELLS
發明專利 I405582 用於傳遞物質之載體複合物及其應用
CARRIER COMPLEXES FOR OBJECT DELIVERY AND APPLICATIONS THEREOF
發明專利 I399434 控制細胞形狀之方法
METHOD OF CONTROLLING CELL SHAPE
發明專利 I387751 用於RhD血型檢驗之套組及使用該套組以檢驗RhD血型之方法
KITS FOR RhD BLOOD TYPE DETERMINATION AND METHOD FOR RhD BLOOD TYPE DETERMINATION BY USING THE SAME
發明專利 I384067 快速篩選生醫材料對細胞影響之細胞培養盤
新型專利 M444156 酒精棉片架組合
發明專利 I461534 促使神經幹細胞增生的培養液及其應用
MEDIUM FOR PROMOTING PROLIFERATION OF NEURAL STEM CELLS AND APPLICATION THEREOF
發明專利 I454291 植入體以及製造其之方法
IMPLANT AND METHOD FOR MANUFACTURING THE SAMEMEDIUM FOR PROMOTING PROLIFERATION OF NEURAL STEM CELLS AND APPLICATION THEREOF
發明專利 I446924 磁性微粒複合物之製作方法
MANUFACTURING METHOD OF MAGNETIC COMPOSITE PARTICLES
發明專利 I432577 用於控制細胞貼附性之方法
METHOD FOR CONTROLLING ATTACHMENT OF CELLS
發明專利 I429421 止鼾貼片
PATCH FOR PREVENTING SNORING
新型專利 M473823 彈性貼布