國立台灣大學 醫學工程學研究所

教師研究成果

林文澧 Win-Li Lin

A. 期刊論文(Journal Papers)

  1. Wu SK, Chiang CF, Hsu YH, Liou HC, Fu WM, Lin WL. “Pulsed-wave low-dose ultrasound hyperthermia selectively enhances nanodrug delivery and improves antitumor efficacy for brain metastasis of breast cancer.” Ultrason Sonochem. 2017 May;36:198-205. doi: 10.1016/j.ultsonch.2016.11.033. Epub 2016 Nov 28.
  2. Chen YC, Chiang CF, Wu SK, Chen LF, Hsieh WY, Lin WL.''Targeting microbubbles-carrying TGFβ1 inhibitor combined with ultrasound sonication induce BBB/BTB disruption to enhance nanomedicine treatment for brain tumors.''J Control Release. 2015 Aug 10;211:53-62. doi: 10.1016/j.jconrel.2015.05.288. Epub 2015 Jun 3.
  3. Wu SK, Chiang CF, Hsu YH, Lin TH, Liou HC, Fu WM, Lin WL,“Short-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer,”Int J Nanomedicine.2014 Sep 19;9:4485-94. doi: 10.2147/IJN.S68347. eCollection 2014. (R/C:15/165;IF:5.824)
  4. Wu SK, Yang MT,, Kang KH, Liou HC, Lu DH, Fu WM, Lin Win-Li, “Targeted Delivery of Erythropoietin by Transcranial Focused Ultrasound for Neuroprotection against Ischemia/Reperfusion-Induced Neuronal Injury:A Long-Term and Short-Term Study,” PLoS One. 2014 Feb 28;9(2):e90107. (R/C:7/56; IF:3.730)
  5. Chen YC, Chiang CF, Chen LF, Liang PC, Hsieh WY, Lin Win-Li, “Polymersomes conjugated with des-octanoyl ghrelin and folate as a BBB-penetrating cancer cell-targeting delivery system,” Biomaterials. 2014 Apr;35(13):4066-81 .(R/C:2/79; IF:7.604)
  6. Chen YC, Chiang CF, Chen LF, Liao SC, Hsieh WY, Lin Win-Li, “Polymersomes conjugated with des-octanoyl ghrelin for the delivery of therapeutic and imaging agents into brain tissues,” Biomaterials 2014 Feb;35(6):2051-65.(R/C:2/79; IF:7.604)
  7. Chou CY, Huang CK, Lu KW, Horng TL, Lin Win-Li, “Investigation of the spatiotemporal responses of nanoparticles in tumor tissues with a small-scale mathematical model,” PLoS One 2013; 8(4):e59135. (R/C:12/85; IF:4.092)
  8. Solovchuk MA, Sheu TWH, Thiriet M, Lin Win-Li, “On a computational study for investigating acoustic streaming and heating during focused ultrasound ablation of liver tumor,” Applied Thermal Engineering 2013; 56: 62-76. (R/C:11/122; IF:2.064)
  9. Huang HW, Liauh CT, Horng TL, Shih TC, Chiang CF, Lin Win-Li, “Effective heating for tumors with thermally significant blood vessels during hyperthermia treatment,” Applied Thermal Engineering 2013; 50: 837-847. (R/C:11/122; IF:2.064)
  10. Lin CY, Li JR, Tseng HC, Wu MF, Lin Win-Li, “Enhancement of focused ultrasound with microbubbles on the treatments of anticancer nanodrug in mouse tumors,” Nanomedicine – Nanotechnology, Biology and Medicine 2012;8:900-907. (R/C:11/112; IF:6.692)
  11. Lin CY, Tseng HC, Shiu HR, Wu MF, Chou CY, Lin Win-Li, “Ultrasound sonication with microbubbles disrupts blood vessels and enhances tumor treatments of anticancer nanodrug,” International Journal of Nanomedicine 2012; 7: 2143-2152. (R/C:70/261; IF:3.130)
  12. Huang HW, Liauh CT, Chou CY, Shih TC, Lin Win-Li, “A fast adaptive power scheme based on temperature distribution and convergence value for optimal hyperthermia treatment,” Applied Thermal Engineering 2012; 37: 103-111. (R/C:11/122, IF:2.064)
  13. Solovchuk MA, Sheu TWH, Lin Win-Li, Kuo I, Thiriet M, “Simulation study on acoustic streaming and convective cooling in blood vessels during a high intensity focused ultrasound ablation,” International Journal of Heat and Mass Transfer 2012; 55: 1261-1270. (R/C:6/122; IF:2.407)
  14. Shih TC, Horng TL, Huang HW, Ju KC, Huang TC, Chen PY, Ho YJ, Lin Win-Li, “Numerical analysis of coupled effects of pulsatile blood flow and thermal relaxation time during thermal therapy,” International Journal of Heat and Mass Transfer 2012; 55: 3763-3773. (R/C:6/122; IF:2.407)
  15. Tsai CK, Chen YS, Wu PC, Hsieh TY, Liu HW, Yeh CY, Lin Win-Li, Chia JS, Liu TM, “Imaging granularity of leukocytes with third harmonic generation microscopy,” Biomedical Optical Express 2012; 3: 2234-2243. (R/C:13/79; IF:2.333)
  16. Chang KH, Ho MC, Yeh CC, Chen YC, Lian FL, Lin Win-Li, Yen JY, Chen YY, “Effectiveness of external respiratory surrogates for in vivo liver motion estimation,” Medical Physics 2012; 39: 5293-5301. (R/C:29/116; IF:2.830)
  17. Chen GS, Lin CY, Jeong JS, Cannata JM, Lin Win-Li, Chang H, Shung KK, “Design and characterization of dual-curvature 1.5-dimensional high-intensity focused ultrasound phased array transducer,” IEEE Trans Ultrason Ferroelectr Freq Control 2012;59:150-155. (R/C:6/30; IF:1.694)
  18. Weng JC, Wu SK, Lin Win-Li, Tseng WY, “Detecting blood-brain barrier disruption within minimal hemorrhage following transcranial focused ultrasound: a correlation study with contrast-enhanced MRI,“ Magnetic Resonance in Medicine 2011; 65: 802-811 (R/C:17/104; IF:3.225)
  19. Lin CY, Liu TM, Chen CY, Huang YL, Huang WK, Sun CK, Chang FH, Lin Win-Li, “Quantitative and qualitative investigation into the impact of focused ultrasound with microbubbles on the triggered release of nanoparticles from vasculature in mouse tumors,” Journal of Controlled Release 2010; 146:291-298 (R/C:14/237; IF: 5.949)
  20. Lin CY, Huang YL, Li JR, Chang FH, Lin Win-Li, “Effects of focused ultrasound and microbubbles on the vascular permeability of nanoparticles delivered into mouse tumors,” Ultrasound in Medicine and Biology 2010; 36: 1460-1469 (R/C:4/28; IF: 2.021)
  21. Huang HW, Liauh CT, Shih TC, Horng TL, Lin Win-Li, “Significance of blood vessels in optimization of absorbed power and temperature distributions during hyperthermia,” International Journal of Heat and Mass Transfer, 2010; 53:5651-5662. (R/C:6/122, IF:2.407)
  22. Weng JC, Wu SK, Yang FY, Lin Win-Li, Tseng WY, “Pulse sequence and timing of contrast enhanced MRI for assessing blood-brain barrier disruption after transcranial focused ultrasound in the presence of hemorrhage,“ Journal of Magnetic Resonance Imaging 2010; 31: 1323-1330 (R/C:27/104; IF:2.770)
  23. Liu YC, Yang MH, Lin Win-Li, Huang CK, Oyang YJ, “A sequence-based hybrid predictor for identifying conformationally ambivalent regions for proteins,” BMC Genomics 2009 10;S22-30. (R/C:43/146; IF:3.759)
  24. Tsai KC, Liao ZK, Yang SJ, Lin Win-Li, Shieh MJ, Huang LH, Chen WS, “Differences in gene expression between sonoporation in tumor and in muscle,” Journal of Gene Medicine 2009; 11:933-940. (R/C:63/146; IF: 2.968)
  25. Tsai KC, Fang SY, Yang SJ, Lin Win-Li, Shieh MJ, Chen WS, “Time dependency of ultrasound-facilitated gene transfection,” Journal of Gene Medicine 2009; 11:729-736. (R/C:63/146; IF:2.968)
  26. Hung CC, Lin SY, Lin SP, Niu DM, LEENC, Cheng WF, Chen CP, Lin Win-Li, Lee CN, SU YN, “Identification of CpG methylation of the SNRPN gene by methylation-specific multiplex PCR,” Electrophoresis 2009; 30: 410-416. (R/C:13/70; IF:3.077)
  27. Cheng TY, Ju KC, Ho CS, Chen YY, Lin Win-Li, “Split-focused ultrasound transducer with multi-directional heating for breast tumor thermal surgery” Medical Physics 2008; 35: 1387-1397 (R/C:29/104; IF: 2.704)
  28. Hung CC, Su YN, Lin CY, Chang YF, Chang CH, Cheng WF, Chen CA, Lee CN, Lin Win-Li, “Comparison of the mismatch-specific endonuclease method and denaturing high-performance liquid chromatography for the identification of HBB gene mutation” BMC Biotechnology 2008; 12: 62-68. (R/C:50/152; IF: 2.723)
  29. Hung CC, Lee CN, Lin CY, Cheng WF, Chen CA, Hsieh ST, Yang CC, Jong YJ, Su YN, Lin Win-Li, “Identification of deletion and duplication genotype of the PMP22 gene by using of PCR-RELP, competitive multiplex PCR and multiplex ligation-dependent probe amplification: a comparison” Electrophoresis 2008; 29: 618-625 (R/C:13/70; IF:3.077)
  30. Yang FY, Fu WM, Lin Win-Li, “Quantitative evaluation of the use of microbubbles with transcranial focused ultrasound on blood-brain barrier disruption,” Ultrasonics Sonochemistry 2008;15: 636-643. (R/C:2/28; IF: 2.993)
  31. Hung CC, Lee CN, Chang CH, Jong YJ, Chen CP, Hsieh WS, Su YN*, Lin Win-Li, “Genotyping of the G1138A mutation of the FGFR3 gene in patients with achondroplasia using high-resolution melting analysis” Clinical Biochemistry 2008 41:162-166 (R/C:8/29; IF: 2.019)
  32. Liu HL, Chang H, Chen WS, Shih TC, Hsiao JK, Lin Win-Li, “Feasibility of transrib focused ultrasound thermal ablation for liver tumors using a spherically curved 2D array: a numerical study” Medical Physics 2007; 34:3436-3448. (R/C:29/104; IF: 2.704)
  33. Liu HL, Chen YY, Lin Win-Li, “A fast and conformal heating scheme for producing large thermal lesions using a 2-D ultrasound phased array,” International Journal of Hyperthermia, 2007; 23:69-82. (R/C:36/104; IF: 2.412)
  34. Shih TC, Yuan P, Lin Win-Li, Kou HS, “Analytical analysis of the Pennes bioheat transfer equation with sinusoidal heat flux condition on skin surface,” Medical Engineering and Physics 2007; 29: 946-953. (R/C:32/59; IF: 1.674)
  35. Fang HY, Tsai KC, Cheng WH, Shieh MJ, Lou PJ, Lin Win-Li, Chen WS, “The effects of power on and off durations of pulsed ultrasound on cancer cells killing,” International Journal of Hyperthermia, 2007;23:371-380. (R/C:36/104; IF: 2.412)
  36. Yang FY, Fu WM, Yang RS, Liu HC, Lin Win-Li, “Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption,” Ultrasound in Medicine and Biology 2007; 33: 1421-1427. (R/C:4/28; IF: 2.021)
  37. Ho CS, Ju KC, Cheng TY, Chen YY, Lin Win-Li, “Thermal therapy for breast tumors by using a cylindrical ultrasound phased array with multifocus pattern scanning: a preliminary numerical study,” Physics in Medicine and Biology 2007; 52:4585-4599. (R/C:25/104; IF:2.781)
  38. Hung CC, Chien SC, Lin CY, Chang CH, Chang YF, Jong YJ, Hsieh ST, Hsieh WS, Liu MS, Lin Win-Li, Lee CN, Su YN, “Use of multiplex PCR and capillary electrophoresis for gene dosage quantification and its biomedical applications for SMN, PMP22, and alpha-globin genes,” Electrophoresis, 2007; 28: 2826-2834. (R/C:13/70; IF:3.077)
  39. Hung CC, Lee CN, Chen CP, Jong YJ, Hsieh WS, Lin Win-Li, Su YN, Hsu SM, “Molecular assay of –alpha3.7 and –alpha4.2 deletions causing alpha-thalassemia by denaturing high-performance liquid chromatography,” Clinical Biochemistry, 2007; 40:817-821. (R/C:8/29; IF: 2.019)
  40. Hung CC, Su YN, Tsao PN, Chen PC, Lin SJ, Lin CH, Mu SC, Liu CA, Chang YC, Lin Win-Li, Hsieh WS, Hsu SM, “Unequal crossover recombination – population screening for PHOX2B gene polyalanine polymorphism using CE,” Electrophoresis 2007; 28: 894-899. (R/C:13/70; IF: 3.077).
  41. Horng TL, Lin Win-Li, Liauh CT, Shih TC, “Effects of pulsatile blood flow in large vessels on thermal dose distribution during thermal therapy,” Medical Physics 2007; 34: 1312-1320. (R/C:29/104; IF: 2.704)

B. 研討會論文(Conference Paper)

  1. Wu SK, Chiang CF, Hsu YH, Liou HC, Fu WM, Lin Win-Li, “Nanodrug delivery and anti-tumor efficacy for brain metastasis of breast cancer enhanced by short-time low-dose ultrasound hyperthermia,”The 2015 World Congress on medical Physics and Biomedical Engineering, Toronto Canada, June 7-12 2015.
  2. Chen YC, Chiang CF, Wu SK, Chen LF, Shieh WY, Lin Win-Li, “Targeting microbubbles-carrying TGFb1 inhibitor combined with ultrasound sonication induce BBB/BTB disruption and pericyte relaxation to enhance nanomedicine treatment for brain tumors” The 8th International Conference on Materials for Advanced Technologies of the Materials Research, Singapore, June 28 - July 3, 2015.
  3. Wu SK, Chiang CF, Hsu YH, Lin TH, Liou HC, Fu WM, Lin Win-Li, “Short-time focused ultrasound hyperthermia enhances liposomal doxolubicin delivery and antitumor efficacy for brain metastasis of breast cancer,” The 6th Asian Congress of Hyperthermic Oncology. Fukui, Japan, Sept. 4-6 2014.
  4. Chen GS, Lin Win-Li, Huang SC, Chang H, “MRI-compatible testing of dual-curvature high-intensity focused ultrasound phased array transducer,” The 6th Asian Congress of Hyperthermic Oncology. Fukui, Japan, Sept. 4-6 2014.
  5. Horng TL, Shih TC, Huang HW, Ju KC, Huang TC, Chen PY, Ho YJ, Lin Win-Li, “Numerical analysis of coupled effects of pulsatile blood flow and thermal relaxation time during thermal therapy, ” The 6th Asian Congress of Hyperthermic Oncology. Fukui, Japan, Sept. 4-6 2014.
  6. Hung-Nien Chen, Guan-Ming Chen, Bo-Sian Lin, Pi-Hsien Lien, Yung-Yaw Chen, Gin-Shin Chen, Lin Win-Li. MRI-compatible Ultrasound Heating System with Ring-shaped Phased Arrays for Breast Tumor Thermal Therapy. 35th Annual International Conference of the IEEE EMBS Osaka, Japan, 3-7 July, 2013.
  7. Yung-Chu Chen, Chi-Feng Chiang, Li-Fang Chen, Wen-Yuan Hsieh, Lin Win-Li. Ultrasound Sonication with Des-octanoyl Ghrelin-Conjugated Microbubbles Enhances the Targeting Delivery and Treatment of Folate-conjugated Polymersomal Doxorubicin for Brain Tumors. P. 82, The 5th Asian Conference on Ultrasound Contrast Imaging. 2013 Annual Convention of Taiwan Society of Ultrasound in Medicine.
  8. Sheng-Kai Wu, MS; Ming-Tao, MD; Kai-Hsiang Kang, MS; Houng-Chi Liou, MS; Dai-Hua Lu, MS; Wen-Mei Fu, PhD; Lin Win-Li, PhD. Targeted Delivery of Erythropoietin by Transcranial Focused reperfusion-induced Neuronal injury: A Long-term and Short-term Study. P. 102, The 5th Asian Conference on Ultrasound Contrast Imaging. 2013 Annual Convention of Taiwan Society of Ultrasound in Medicine.
  9. Hsiao-Hsuan Huung, Yu-Hone Hsu, Tzu-Hung Lin, Sheng-Kai Wu, Lin Win-Li. Enhancementof Focused Ultrasound with Microbubbles on the Delivery and Treatments of Anticancer Nanodrug in Different Stages of Brain Tumors. P. 103, The 5th Asian Conference on Ultrasound Contrast Imaging. 2013 Annual Convention of Taiwan Society of Ultrasound in Medicine.
  10. Chen GS, Lin CY, Jeong JS, Cannata JM, Chang H, Shung KK, Lin Win-Li. Design and characterization of dual-curvature 1.5-dimensional focused ultrasound phase-array transducer for tumor thermal therapy. P. 171, 11th Int. Congress Hyperthermic Oncology. Aug. 28~31, 2012, Kyoto, Japan.
  11. Lin BS, Lien PH, Chen GS, Hwang SC, Chen SF, Chen YY, Lin Win-Li. MRI-compatible ring-typed ultrasound phased-array transducer for breast tumor thermal therapy. P. 181, 11th Int. Congress Hyperthermic Oncology. Aug. 28~31, 2012, Kyoto, Japan.
  12. Huang HW, Chiang CF, Lin Win-Li, “A fast adaptive power scheme based on temperature distribution and convergence value for optimal hyperthermia treatment,” p. 170, 11th Int. Congress Hyperthermic Oncology. Aug. 28~31, 2012, Kyoto, Japan.
  13. Huang HW, Chiang CF, Lin Win-Li, “Effective heating for tumors with thermally significant blood vessels during hyperthermia treatment,” p. 170, 11th Int. Congress Hyperthermic Oncology. Aug. 28~31, 2012, Kyoto, Japan.
  14. Chiang CF, Shiu HR, Tseng HC, Chang FH, Lin Win-Li, “Treatment enhancement of ultrasound-mediated nanodrug delivery in combination with hyperthermia,” p. 150, 11th Int. Congress Hyperthermic Oncology. Aug. 28~31, 2012, Kyoto, Japan.
  15. Wu HY, Lee YS, Lu KW, Wu SK, Wu WC, Lin Win-Li. “Focused ultrasound with microbubbles transiently opens the blood-brain barrier and heparin significantly enhances the delivery of macromolecules into the brain tissue.” June 10-13, 2012, 12th Int. Symp. On Therapeutic Ultrasound, Heidelberg, Germany.
  16. Wu SK, Fu WM, Liou HC, Yang MT, Lin Win-Li, “Enhancement of neuroprotective effects of erythropoietin by focused ultrasound with microbubbles in ischemia-reperfusion injured rats,” p. 20, 11th Int. Symp. Therapeutic Ultrasound 2011: April 11-13 , New York, USA.
  17. Tseng HC, Shiu HR, Wu MF, and Lin Win-Li, “Effects of ultrasound sonication with microbubbles on the tumor growth response in mouse ear model treated with liposomal doxorubicin,” p.59, 11th Int. Symp. Therapeutic Ultrasound 2011: April 11-13 ,New York, USA.
  18. Chang CH, Jou RC, Lin Win-Li, “Predicting the optimal estimated pressure of BBB disruption from the pressure attenuation of skull thickness by focused ultrasound-mediated microbubbles,” p. 94, 11th Int. Symp. Therapeutic Ultrasound 2011: April 11-13, New York, USA.
  19. Cheng CF, Lin Win-Li, Chen YY, “Effects of tracking error on lesion formation in high intensity focused ultrasound liver tumor tracking treatment,” p. 50, 10th Int. Symp. Therapeutic Ultrasound 2010: June 9-12, Tokyo, Japan.
  20. Chang CH, Weng JC, Jou RC, Tseng WYI, Lin Win-Li, “Blood-brain barrier disruption within minimal hemorrahage using multi-sonication of focused ultrasound-mediated microbubbles under MR monitoring,” P. 92, 10th Int. Symp. Therapeutic Ultrasound 2010: June 9-12, Tokyo, Japan.
  21. Lin CY, Huang YL, Chang FH, Lin Win-Li, “Parametric study of focused ultrasound and microbubbles on the vascular permeability of nanoparticles delivered into mouse tumors,” P. 95, 10th Int. Symp. Therapeutic Ultrasound 2010: June 9-12, Tokyo, Japan.
  22. Wu HY, Huang HY, Weng JC, Lu KW, Wu SK, Lin Win-Li, “Enhancement and monitoring of nanoparticle delivery into brain tissue using additional sonication and iron oxide,” P. 104, 10th Int. Symp. Therapeutic Ultrasound 2010: June 9-12, Tokyo, Japan.
  23. Chen GS, Chang H, Kuo YY, Lin Win-Li, Chen WS, Tseng WY, “Design and fabrication of a wide-aperture HIFU annular array transducer for the treatment of deep-seated tumors,” P. 116, 10th Int. Symp. Therapeutic Ultrasound 2010: June 9-12, Tokyo, Japan.
  24. Wu SK, Lee PC, Lee YS, Wu XY, Fu WM, Lin Win-Li, “Bilateral-array focused ultrasound transducer with dual-freuency mode for blood-brain barrier opening in presence of microbubbles,” p. 105, 11th Int. Congress of the IUPESM Medical Physics and Biomedical Engineering World Congress 2009, Sept 7-11, Munich, Germany.
  25. Lu KW, Huang CH, Wang CC, Lin Win-Li, “Disruption of microvessels by focused ultrasound with microbubbles to cause the extravasation of macromolecules and observed by two-photon fluorescence microscopy,” p. 109, 11th Int. Congress of the IUPESM Medical Physics and Biomedical Engineering World Congress 2009, Sept 7-11, Munich, Germany.
  26. Liu YW, Lin SY, Chen YY, Huang HW, Lin Win-Li, “Confocal ultrasound bilateral-array with dual-frequency driving and contrast agent for thermal therapy,” PS5, Annual meeting for Society for Thermal Medicine USA, 2009, April 4-7,Tucson, Arizona, USA.
  27. Hsu MC, Liauh CT, Chen YY, Chang H, Lin Win-Li, “dual ultrasound curved phased-arays with energy deposition density method for respiratory-gated tumor thermal therapy,” PS6, Annual meeting for Society for Thermal Medicine USA, 2009, April 4-7, Tucson, Arizona, USA.
  28. Lee YS, Hu S, Wu XY, Lin Win-Li, “Delivery improvement into brain tissue with ultrasound sonication after blood-brain barrier opened temporarily by focused ultrasound with microbubbles,” P142, 9th Int. Symp. Therapeutic Ultrasound 2009: Sept. 22-25, Aix-en-Provence, France.
  29. Lin CY, Chen C, Liu TM, Lin Win-Li, “Qualitative and quantitative evaluation of nanoparticles delivery into tumor tissue enhanced by focused ultrasound with microbubbles,” P95, 9th Int. Symp. Therapeutic Ultrasound 2009: Sept. 22-25, Aix-en-Provence, France.
  30. Lin KH, young SY, Hsu MC, Chen YY, Lin Win-Li,”Focused ultrasound thermal therapy system with ultrasound image guidance and temperature measurement feedback,” 30th IEEE Eng. Med. Biol. Society, 2008; Aug. 23-28, Annual International Conf. Vancouver, Canada.
  31. Liu YW, Lin SY, Wu SK, Chen YY, Lin Win-Li, “Confocal ultrasound with dual-frequency driving and contrast agent for thermal therapy,” P. 71, 8th Int. Symp. Therapeutic Ultrasound 2008: Sept. 10-13, Minneapolis, Minnesoda, USA.
  32. Chiang SW, LUDY, Tang CH, Fu WM, Lin Win-Li, “Effects of low intensity pulsed ultrasound on microglia activation and neuroprophic factor expression in astrocytes,” P. 73, 8th Int. Symp. Therapeutic Ultrasound 2008: Sept. 10-13, Minneapolis, Minnesoda, USA.

C. 專書及專書論文(Books and chapter in Book)


D. 技術報告及其他(Technological transfer and others)

標準制訂(經濟部中央標準局委託)
  1. 超音波熱療儀器
  2. 超音波診斷裝置性能測試方法通則
  3. A Mode 超音波診斷裝置
  4. B Mode 超音波診斷裝置
  5. 電子式線性掃瞄超音波診斷裝置
  6. M Mode 超音波診斷裝置
  7. 超音波Doppler 胎兒診斷裝置

E. 專利(Patents)

  1. 劉浩澧, 林文澧, 張恕: Medical treatment using an ultrasound phased array. USA 12/033,370.
  2. 許銘權, 張恕, 林文澧: Generating gating signals for thermal therapy. USA 12/241,231.
  3. 陳景欣, 林文澧, 張恕: Dual-curvature phased array high-intensity focused ultrasound transducer for tumor therapy. USA 12/535,235.
  4. 劉浩澧, 林文澧, 張恕: 一種以超音波相位陣列達到穿透肋骨治療之系統及方法. ROC 97105878.
  5. 陳景欣, 林文澧, 張恕: Ring-shaped phased-array focused-ultrasound probe for thermal treatment of breast cancer. USA (under application)