國立臺灣大學醫學工程學系

Publications: (2019-2025)

1. Rob M A de Bie, Regina Katzenschlager, Bart E K S Swinnen, Marina Peball, Shen-Yang Lim, Tiago A Mestre, Santiago Perez Lloret, Miguel Coelho, Camila Aquino, Ai Huey Tan, Veronica Bruno, Joke M Dijk, Beatrice Heim, Chin-Hsien Lin, Linda Azevedo Kauppila, Irene Litvan, René Spijker, Klaus Seppi, João Costa, Cristina Sampaio, Susan H Fox, Monty A Silverdale. Update on Treatments for Parkinson’s Disease Motor Fluctuations – An MDS Evidence-Based Medicine Review. Movement Disorders 2025 2025 Mar 8. doi: 10.1002/mds.30162.
2. Chia-Yu Li, Ling-Yun Fan, Chin-Hsien Lin, Chaur-Jong Hu, Ming-Jang Chiu. Ultrasensitive Assays Detect Different Conformations of Plasma β Amyloids. ACS Omega 2025 Feb 11;10(7):7256-7263.
3. Garcia JJB, Cabataña GJ Jr, Ditan I, Separa KJNJ, Rocha-Tulagan II, Lin HI, Lin CH, Supnet-Wells MLD, Diaz AF, Ng AR, Jamora RDG, Saranza G. Recognizing familial Huntington's disease in an Asian cohort: Insights from the Philippines. eNeurologicalSci. 2025 Jan 26;38:100558
4. Yi-Cheng Tai, Malan Edward, Chin-Hsien Lin*.A 69-year-old male with subacute gait disturbance; Blastocystis hominis causing extensive colitis with thiamine deficiency. Movement Disorders Clinical Practice 2025 in press
5. Chia-Yu Li, Ling-Yun Fan, Chin-Hsien Lin, Chaur-Jong Hu, and Ming-Jang Chiu*. Ultrasensitive Assays Detect Different Conformations of Plasma β Amyloids. ACS Omega, 2025, in press.
6. Chih-Hao Chen,* Te-Wei Wang,* Yu-Wen Cheng, Yung-Tsai Chu, Mei-Fang Cheng, Ya-Fang Chen, Chin-Hsien Lin*, Sung-Chun Tang*. Parkinsonism in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: Clinical Features and Biomarkers. Journal of Stroke 2025;27(1):122-127
7. Solijon KLK, Engkong RO, Cavan BCV, Ong LY, Chen YH, Lin HI, Lin CH, Saranza G. Compound heterozygous TMEM67 biallelic variants including a novel frameshift mutation in two Filipino adolescent siblings with Joubert syndrome. J Neural Transm (Vienna). 2025 Jan 23. doi: 10.1007/s00702-025-02885-4.
8. Mollenhauer B*, Lin CH. Movement disorders in 2024: peripheral and outside the box. Lancet Neurol 2025 Jan;24(1):15-16.
9. Cheng-Wei Huang, Hsin-Yun Tsai, Yi-Hsuan Lin, Wen-Wei Lin, Chin-Hsien Lin*, Ming-Tsung Tseng*.Striatal-cortical dysconnectivity underlies somatosensory deficits in Parkinson's disease: Insights from rhythmic auditory-motor training. Neurobiol Dis 2025 Jan:204:106778.
10. Wee Shin Lim, Shu-I Chiu, Pei-Ling Peng, Jyh-Shing Roger Jang, Sol-Hee Lee, Chin-Hsien Lin*, Han-Joon Kim* A cross-language speech model for detection of Parkinson’s disease. Journal of Neural Transmission (Vienna). 2025 Apr;132(4):579-590.
11. Szu-Ju Chen, Shih-Chun Pan, Chih-Da Wu, Hsun Li, Yue Leon Guo*, Chin-Hsien Lin.* Long-term Exposure to Multiple Air Pollutants and Risk of Parkinson’s Disease: A Population-based Multi-pollutant Model Study. Journal of Neurology, Neurosurgery and Psychiatry 2024 Dec 27:jnnp-2024-334825. doi: 10.1136/jnnp-2024-334825.
12. Cheng-Hsuan Li, Sung-Pin Fan, Ming-Chieh Shih, Yi-Hsin Weng, Ta-Fu Chen, Hsun Li, Mei-Fang Cheng, Ming-Che Kuo, Pei-Ling Peng, Makoto Higuchi, Ing-Tsung Hsiao*, Kun-Ju Lin*, Chin-Hsien Lin* Subcortical tau burden correlates with regional brain atrophy and plasma markers in four-repeat tauopathy parkinsonism. Journal of Parkinson’s disease 2024 Dec 8:1877718X241298192. doi: 10.1177/1877718X241298192. 
13. Sung-Pin Fan, Ya-Fang Chen, Cheng-Hsuan Li, Yih-Chih Kuo, Ni-Chung Lee, Yin-Hsiu Chien, Wuh-Liang Hwu, Tai-Chung Tseng, Tung-Hung Su, Chien-Ting Hsu, Huey-Ling Chen, Chin-Hsien Lin*, Yen-Hsuan Ni*. Topographical metal burden correlates with brain atrophy and clinical severity in Wilson’s disease. Neuroimage 2024, 2024 Oct 1;299:120829. doi: 10.1016/j.neuroimage.2024.120829. Epub 2024 Sep 2.
14. Jagota P, Phutrakool P, Kamble N, Dang THT, Aldaajani Z, Hatano T, Hoskere Sreenivasa DK, Tripura T, Kukkle PL, Jeon B, Nishikawa N, Oji Y, Tran TN, Susatia F, Fabbri M, Leung C, Alonso Canovas A, Kamel WA, Pal PK, Rakesh K, Abu Snineh M, Chairangsaris P, Lolekha P, Jamora RDG, Mohamed Ibrahim N, Desa SHM, Tan AH, Toh TS, Obaid M, Fung VSC, Lang A, Lin CH, Regragui W, Bouslam N, Bhidayasiri R. Exercise Habits in People with Parkinson's: A Multinational Survey. Mov Disord Clin Pract 2024 Aug 29. doi: 10.1002/mdc3.14197.
15. Norlinah Mohamed Ibrahim* and Chin-Hsien Lin*. Early Onset Parkinsonism: Differential diagnosis and what not to miss. Parkinsonism & Related Disorders. 2024 Aug 15:107100. doi: 10.1016/j.parkreldis.2024.107100.
16. Peng-Hsiang Liao, Hsiao-Yen Tung, Wee Shin Lim, Jyh-Shing Roger Jang, Hsun Li, Chia-Tung Shun, Han-Mo Chiu, Ming-Shiang Wu, Chin-Hsien Lin*. Impaired gut barrier integrity and reduced colonic expression of free fatty acid receptors in patients with Parkinson’s disease. Neurological Sciences. 2024 Nov;45(11):5297-5307.
17. Sung-Ju Hsueh, Chin-Hsien Lin, Ni-Chung Lee, Tung-Ming Chang, Sung-Pin Fan, Wan-De Huang, Yea-Huey Lin, Li-Kai Tsai, Yin-Hsiu Chien, Ming-Jen Lee, Wuh-Liang Hwu, Hsueh Wen Hsueh*, Chih-Chao Yang*. Unique clinical and electrophysiological features in the peripheral nerve system in patients with sialidosis - a case series study. Orphanet J Rare Dis 2024 May 24;19(1):217.
18. Lin YH, Wang LW, Chen YH, Chan YC, Hu SH, Wu SY, Chiang CS, Huang GJ, Yang SD, Chu SW, Wang KC, Lin CH, Huang PH, Cheng HJ, Chen BC, Chu LA. Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain. Elife. 2024 May 22;13:RP93212. doi: 10.7554/eLife.93212.
19. Chang JC, Chang HS, Chao YC, Huang CS, Lin CH, Wu ZS, Chang HJ, Liu CS, Chuang CS. Formoterol Acting via β2-Adrenoreceptor Restores Mitochondrial Dysfunction Caused by Parkinson's Disease-Related UQCRC1 Mutation and Improves Mitochondrial Homeostasis Including Dynamic and Transport. Biology (Basel). 2024;13(4):231.
20. Huan-Yun Chen, Chia-Yu Liao, Hsun Li. Yi-Ci Ke Lin, Chin-Hsien Lin,* Teng, Shu-Chun*. ATM-mediated co-chaperone DNAJB11 phosphorylation facilitates α-synuclein folding upon DNA double-stranded breaks. NAR Molecular Medicine. 2024 in press
21. Pin-Shiuan Chena, Ying-Fa Chen, Jian-Ying Chiu, Meng-Chen Wu, MD, Chun-Hwei Tai, Yung-Yee Chang, Min-Yu Lan, Han-I Lin, Ni-Chung Lee, Chin-Hsien Lin*. Genetic analysis of IRF2BPL in a Taiwanese dystonia cohort: the genotype and phenotype correlation. Annals of Clinical and Translational Neurology 2024 Jun;11(6):1557-1566. 
22. Tiago F Outeiro, Lorraine V Kalia, Erwan Bezard, Juan Ferrario, Chin-Hsien Lin, Mohamed Salama, David G Standaert, Lolade Taiwo, Ryosuke Takahashi, Miquel Vila, Brit Mollenhauer, Per Svenningsson*; MDS Basic Science Special Interest Group Steering Committee. Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice. Mov Disord 2024 39(6):929-933.
23. Chih-Hsin Ou-Yang, Pin-Shiuan Chen, Chin-Hsien Lin*. Generation of a human induced pluripotent stem cell line NTUHi004-A from a patient with Leigh syndrome harboring a homozygous missense mutation c.836 T > G (p.Met279Arg) in NDUFAF5 gene. Stem Cell Research 2024 Apr:76:103379.
24. Gary Han Chang , Meng-Yun Wu , Ling-Hui Yen , Da-Yu Huang , Ya-Hui Lin , Yu-Ru Luo , Ya-Ding Liu , Bin Xu , Kam W. Leong , Wen-Sung Lai , Ann-Shyn Chiang , Kuo-Chuan Wang , Chin-Hsien Lin , Shih-Luen Wang , Li-An Chu*. Isotropic Multi-Scale Neuronal Reconstruction from High-Ratio Expansion Microscopy with Contrastive Unsupervised Deep Generative Models. Computer Methods and Programs in Biomedicine. 2024 Feb;244:107991.
25. Ya-Lan Chang, Chan-Chih Yang, Yun-Yu Huang, Yi-An Chen, Chia-Wei Yang, Chia-Yu Liao, Hsun Li, Ching-Shyi Wu, Chin-Hsien Lin*, Shu-Chun Teng*. The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation. BMC Biol 2023 Dec 18;21(1):293.
26. Szu-Ju Chen#, Yu-Jun Wu#, Chieh-Chang Chen, Yu-Wei Wu, Jyh-Ming Liou, Ming-Shiang Wu, Ching-Hua Kuo*, Chin-Hsien Lin*. Plasma metabolites of aromatic amino acids associate with clinical severity and gut microbiota of Parkinson’s disease. npj Parkinson's Disease 2023 Dec 14;9(1):165. doi: 10.1038/s41531-023-00612-y.
27. Qing Wang, Hang Zhou, Bibiao Shen, Zifeng Huang, Shuzhen Zhu, Wanlin Yang, Fen Xie, Yuqi Luo, Feilan Yuan, Zhaohua Zhu, Chao Deng, Wenhua Zheng, Chengwu Yang, Chin-Hsien Lin, Bin Xiao, and EK Tan. Mendelian randomization reveals association between retinal thickness and non-motor symptoms of Parkinson's disease. npj Parkinson's Disease 2023 Dec 13;9(1):163.
28. Vollstedt EJ, Madoev H, Aasly A, Ahmad-Annuar A, Al-Mubarak B, Alcalay RN, Alvarez V, Amorin I, Annesi G, Arkadir D, Bardien S, Barker RA, Barkhuizen M, Basak AN, Bonifati V, Boon A, Brighina L, Brockmann K, Carmine Belin A, Carr J, Clarimon J, Cornejo-Olivas M, Correia Guedes L, Corvol JC, Crosiers D, Damásio J, Das P, de Carvalho Aguiar P, De Rosa A, Dorszewska J, Ertan S, Ferese R, Ferreira J, Gatto E, Genç G, Giladi N, Gómez-Garre P, Hanagasi H, Hattori N, Hentati F, Hoffman-Zacharska D, Illarioshkin SN, Jankovic J, Jesús S, Kaasinen V, Kievit A, Klivenyi P, Kostic V, Koziorowski D, Kühn AA, Lang AE, Lim SY, Lin CH, Lohmann K, Markovic V, Martikainen MH, Mellick G, Merello M, Milanowski L, Mir P, Öztop-Çakmak Ö, Pimentel MMG, Pulkes T, Puschmann A, Rogaeva E, Sammler EM, Skaalum Petersen M, Skorvanek M, Spitz M, Suchowersky O, Tan AH, Termsarasab P, Thaler A, Tumas V, Valente EM, van de Warrenburg B, Williams-Gray CH, Wu RM, Zhang B, Zimprich A, Solle J, Padmanabhan S, Klein C. Establishing an online resource to facilitate global collaboration and inclusion of underrepresented populations: Experience from the MJFF Global Genetic Parkinson's Disease Project. PLoS One. 2023 Oct 3;18(10):e0292180.
29. Pin-Shiuan Chen, Ni-Chung Lee, Chieh-Ju Sung, Ya-Wen Liu, Wen-Chin Weng, MD, Pi-Chuan Fan, Wang-Tso Lee, Yin-Hsiu Chien, Chao-Szu Wu, Yueh-Feng Sung, Ming-Chen Tsai, Yi-Chung Lee, Hsueh-Wen Hsueh, Sabrina Mai-Yi Fan, Meng-Chen Wu, Hsun Li, Huan-Yun Chen, Han-I Lin, Chih-Hsin Ou-Yang, Wuh-Liang Hwuh, Chin-Hsien Lin.* Phenotypic heterogeneity in patients with mutations in the mitochondrial complex I assembly gene NDUFAF5. Movement Disorders 2023 Dec;38(12):2217-2229.
30. John Yu, Hsiu-Hui Tsai, Hsiao-Jung Kao, Ming-Wei Kuo, Chin-Hsien Lin, Chin-Min Chang, Yi-Yin Chen, Hsiao-Huei Chen, Pui-Yan Kwok, and Alice Yu. Whole genomic analysis reveals atypical non-homologous off-target large structural variants induced by CRISPR-Cas9-mediated genome editing. Nature Communications 2023 Aug 25;14(1):5183. doi: 10.1038/s41467-023-40901-x.
31. Yung-Tsai Chu, Chin-Feng Yu, Sung-Pin Fan, Ta-Fu Chen, Ming-Jang Chiu, Jyh-Shing Roger Jang, Shu-I Chiu*, Chin-Hsien Lin*.Substantia nigra nigrosome-1 imaging correlates with the severity of motor symptoms in Parkinson's disease. J Neurol Sci 2023 Aug 15;451:120731.
32. Meng-Chen Wu, Yung-Yee Chang, Min-Yu Lan, Ying-Fa Chen, Chun-Hwei Tai, Szu-Ju Chen, Chin-Hsien Lin*. Blood neurofilament light chain as a surrogate marker for dystonia. European Journal of Neurology 2023 Oct;30(10):3098-3104.
33. Yi-Cheng Tai, Peng-Hsiang Liao, Valentina Leta, Chin-Hsien Lin*, K Ray Chaudhuri. Irritable bowel syndrome based on Rome IV diagnostic criteria associates with non-motor symptoms of Parkinson’s disease. Parkinsonism & Related Disorders. 2023 Aug;113:105496.
34. Ibrahim NM, Jagota P, Pal PK, Bhidayasiri R, Lim SY, Ugawa Y, Aldaajani Z, Jeon B, Fujioka S, Lee JY, Kukkle PL, Shang H, Phokaewvarangkul O, Diesta C, Shambetova C, Lin CH. Historical and more common nongenetic movement disorders from Asia. J Mov Disord. 2023 Sep;16(3):248-260.
35. Jagota P, Ugawa Y, Aldaajani Z, Ibrahim NM, Ishiura H, Nomura Y, Tsuji S, Diesta C, Hattori N, Onodera O, Bohlega S, AlDin ASN, Lim SY, Lee JY, Jeon B, Pal PK, Shang H, Fujioka S, Kukkle PL, Phokaewvarangkul O, Lin CH, Shambetova C, Bhidayasiri R. Nine Hereditary Movement Disorders First Described in Asia: Their History and Evolution. J Mov Disord. 2023 Sep;16(3):231-247.
36. Priya Jagota, Shen-Yang Lim, Pramod Kumar Pal, Jee-Young Lee, Prashanth Lingappa Kukkle, Shinsuke Fujioka, Huifang Shang, Onanong Phokaewvarangkul, Roongroj Bhidayasiri, Mohamed Ibrahim Norlinah, FRCPE, Yoshikazu Ugawa, Zakiyah Aldaajani, Beomseok Jeon, Cid Diesta, Cholpon Shambetova, Chin-Hsien Lin. Genetic Movement Disorders Commonly Seen in Asians. Movement Disorders Clinical Practice, 2023 May 8;10(6):878-895.
37. Huan-Yun Chen, Han-I Lin, Chia-Lang Hsu, Pei-Lung Chen, Cheng‑Yen Huang, Shu-Chun Teng*, Chin-Hsien Lin*. A novel C19orf12 frameshift mutation in a MPAN pedigree impairs mitochondrial function and connectivity leading to neurodegeneration. Parkinsonism Relat Disord. 2023 Apr:109:105353.
38. Sung-Pin Fan, Yih-Chih Kuo, Ni-Chung Lee, Yin-Hsiu Chien, Wuh-Liang Hwu, Yu-Hsuan Huang, Han-I Lin, Tai-Chung Tseng, Tung-Hung Su, Shiou-Ru Tzeng, Chien-Ting Hsu, Huey-Ling Chen, Chin-Hsien Lin*, Yen-Hsuan Ni*. Clinical Characteristics, Genetic Features, and Long-Term Outcome of Wilson’s Disease in a Taiwanese Population: An 11-Year Follow-Up Study. Journal of Movement Disorders, 2023 May;16(2):168-179.
39. Vollstedt EJ, Schaake S, Lohmann K, Padmanabhan S, Brice A, Lesage S, Tesson C, Vidailhet M, Wurster I, Hentati F, Mirelman A, Giladi N, Marder K, Waters C, Fahn S, Kasten M, Brüggemann N, Borsche M, Foroud T, Tolosa E, Garrido A, Annesi G, Gagliardi M, Bozi M, Stefanis L, Ferreira JJ, Correia Guedes L, Avenali M, Petrucci S, Clark L, Fedotova EY, Abramycheva NY, Alvarez V, Menéndez-González M, Jesús Maestre S, Gómez-Garre P, Mir P, Belin AC, Ran C, Lin CH, Kuo MC, Crosiers D, Wszolek ZK, Ross OA, Jankovic J, Nishioka K, Funayama M, Clarimon J, Williams-Gray CH, Camacho M, Cornejo-Olivas M, Torres-Ramirez L, Wu YR, Lee-Chen GJ, Morgadinho A, Pulkes T, Termsarasab P, Berg D, Kuhlenbäumer G, Kühn AA, Borngräber F, de Michele G, De Rosa A, Zimprich A, Puschmann A, Mellick GD, Dorszewska J, Carr J, Ferese R, Gambardella S, Chase B, Markopoulou K, Satake W, Toda T, Rossi M, Merello M, Lynch T, Olszewska DA, Lim SY, Ahmad-Annuar A, Tan AH, Al-Mubarak B, Hanagasi H, Koziorowski D, Ertan S, Genç G, de Carvalho Aguiar P, Barkhuizen M, Pimentel MMG, Saunders-Pullman R, van de Warrenburg B, Bressman S, Toft M, Appel-Cresswell S, Lang AE, Skorvanek M, Boon AJW, Krüger R, Sammler EM, Tumas V, Zhang BR, Garraux G, Chung SJ, Kim YJ, Winkelmann J, Sue CM, Tan EK, Damásio J, Klivényi P, Kostic VS, Arkadir D, Martikainen M, Borges V, Hertz JM, Brighina L, Spitz M, Suchowersky O, Riess O, Das P, Mollenhauer B, Gatto EM, Petersen MS, Hattori N, Wu RM, Illarioshkin SN, Valente EM, Aasly JO, Aasly A, Alcalay RN, Thaler A, Farrer MJ, Brockmann K, Corvol JC, Klein C; MJFF Global Genetic Parkinson's Disease Study Group. Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort. Mov Disord. 2023 Feb;38(2):286-303.
40. Chen PS, Wu MC, Tai CH, Chang YY, Lan MY, Chen YF, Lin HI, Lee NC, Lin CH*. Genetic analysis of IMPDH2 gene in Taiwanese patients with isolated or combined dystonia. Parkinsonism Relat Disord. 2023 Jan 17;107:105294.
41. Cheng-Hsuan Li, Ni-Chung Lee, Kun-Ju Lin, Ing-Tsung Hsiao, Yi-Hsin Weng, Chin-Hsien Lin*. The MAPT p.P301L mutation presents as a rare early-onset corticobasal syndrome: a case report. Neurology Asia 2022, in press.
42. Chia-Mei Chu, Hsin-Hui Yu, Tsai-Ling Kao, Yi-Hsuan Chen, Hsuan-Hsuan Lu, En-Ting Wu, Yun-Li Yang, Chin-Hsien Lin, Shin-Yu Lin, Meng-Ju Melody Tsai, Yin-Hsiu Chien, Wuh-Liang Hwu, Wen-Pin Chen, Ni-Chung Lee*, Chi-Kang Tseng*. A missense variant in the nuclear localization signal of DKC1 causes Hoyeraal-Hreidarsson syndrome. npj Genomic Medicine 2022 Oct, 30;7(1):64.
43. Wee Shin Lim,^# Shu-I Chiu, ^# Meng-Ciao Wu, Shu-Fen Tsai, Pu-He Wang, Kun-Pei Lin, Yung-Ming Chen, Pei-Ling Peng, Yung-Yaw Chen, Jyh-Shing Roger Jang, Chin-Hsien Lin.* An integrated biometric voice and facial features for early detection of Parkinson’s disease. npj Parkinson’s Disease 2022 Oct 29;8(1):145.
44. Lin CH*, Lai HC, Wu MS. Gut-oriented disease modifying therapy for Parkinson's disease. J Formos Med Assoc. 2023 Jan;122(1):9-18.
45. Feng Liang, Cheng-Yu Chen, Yun-Pu Li, Yi-Ci Ke, En-Pong Ho, Chih-Fan Jeng, Chin-Hsien Lin*, Shih-Kuo Chen*. Early dysbiosis and dampened gut microbe oscillation precede motor dysfunction and neuropathology in animal models of Parkinson’s disease. Journal of Parkinson’s Disease, 2022;12(8):2423-2440.
46. Szu-Ju Chen, Chin-Hsien Lin*. Gut microenvironmental changes as a potential trigger in Parkinson’s disease through the gut–brain axis. Journal of Biomedical Science, 2022 Jul 27;29(1):54.
47. Cheng-Hsuan Li, Ta-Fu Chen, Pei-Ling Peng, Chin-Hsien Lin*. A task-specific cognitive domain decline is correlated with plasma and neuroimaging markers in patients with Parkinson’s disease. Journal of Neurology, 2022 Dec;269(12):6530-6543.
48. Chih-Hsin Ou-Yang, Han-I Lin, Chin-Hsien Lin*. Generation of a human induced pluripotent stem cell line NTUHi002-A from a patient with aceruloplasminemia harboring a homozygous splicing mutation c.607+1 delG in CP gene. Stem Cell Research, 2022, Aug;63:102856.
49. Kuo MC, Lu YC, Tai CH, Soong BW, Hu FC, Chen ML, Lin CH, Wu RM. COQ2 and SNCA polymorphisms interact with environmental factors to modulate the risk of multiple system atrophy and subtype disposition. Eur J Neurol. 2022 Oct;29(10):2956-2966.
50. Chen YA, Wu RM, Sheu CH, Lin CH, Huang CY. Attentional focus effect on dual-task walking in Parkinson's disease with and without freezing of gait. Geroscience. 2023 Feb;45(1):177-195.
51. Chao-Wen Lin, Tzu-Ting Lai, Szu-Ju Chen, Chin-Hsien Lin*. Elevated α-synuclein and NfL levels in tear fluids and decreased retinal microvascular densities in patients with Parkinson’s disease. GeroScience 2022 Jun;44(3):1551-1562.
52. Lucia Yi-Ru Chung, Yi-Ting Lin, Chi Liu, Yi-Cheng Tai, Han-Yi Lin, Chin-Hsien Lin*, Ching-Chow Chen*. Neuroinflammation Upregulated Neuronal Toll-Like Receptors 2 and 4 to Drive Synucleinopathy in Neurodegeneration. Front Pharmacol. 2022 Mar 24;13:845930. doi: 10.3389/fphar.2022.845930.
53. Szu-Ju Chen, Chieh-Chang Chen, Hsin-Yu Liao, Yu-Wei Wu, Jyh-Ming Liou, Ming-Shiang Wu, Ching-Hua Kuo, Chin-Hsien Lin*. Alteration of Gut Microbial Metabolites in the Systemic Circulation of Patients with Parkinson's Disease. J Parkinsons Dis. 2022 Mar 23. 12(4):1219-1230.
54. I-Ting Lin, Ni-Chung Lee, Sung-Pin Fan, Chang-Jin Huang, PoWei Cheng, Jyh-Horng Chen, Chin-Hsien Lin*. A case of senile-onset progressive hemiballism and cognitive decline with diffuse brain iron accumulations. Parkinsonism & Related Disorders 2022 May:98:114-117.
55. Peng-Hsiang Liao, HanLin Chiang, Chia-Tung Shun, Jen-Fan Hang, Han-Mo Chiu, Ming-Shiang Wu, Chin-Hsien Lin*. Colonic LRRK2 expression is increased and associated with disease severity in patients with Parkinson’s disease. Frontiers in Aging Neuroscience 2022, Jan 17;13:819373. doi: 10.3389/fnagi.2021.819373. eCollection 2021.
56. Jeng-Lin Li, Tai-Yi Lin, Po-Lin Chen, Shu-Yi Huang, Chun-Hong Chen, Chin-Hsien Lin, Chih-Chiang Chan.* Mitochondrial function and Parkinson's disease: from the perspective of the electron transport chain. Frontiers in Molecular Neuroscience 2021 Dec 9;14:797833. doi: 10.3389/fnmol.2021.797833.
57. Szu-Ju Chen, Chieh-Chang Chen, Hsin-Yu Liao, Ya-Ting Lin, Yu-Wei Wu, Jyh-Ming Liou, Ming-Shiang Wu, Ching-Hua Kuo*, Chin-Hsien Lin*. Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Parkinson Disease Patients. Neurology . 2022 Feb 22;98(8):e848-e858.
58. Toh TS, Chong CW, Lim SY, Bowman J, Cirstea M, Lin CH, Chen CC, Appel-Cresswell S, Finlay BB, Tan AH. Gut microbiome in Parkinson's disease: New insights from meta-analysis. Parkinsonism Relat Disord. 2022;94:1-9.
59. Meng-Chen Wu, Yung-Yee Chang, Min-Yu Lan, Ying-Fa Chen, Chun-Hwei Tai, Yung-Feng Lin, Shih-Feng Tsai, Pei-Lung Chen, Chin-Hsien Lin*. A clinical and integrated genetic study of isolated and combined dystonia in Taiwan. The Journal of Molecular Diagnostics 2022 Mar;24(3):262-273.
60.  Chin-Hsien Lin*, Han-Yi Lin, En-Pong Ho, Yi-Ci Ke, Mei-Fang Cheng, Chyng-Yann Shiue, Chi-Han Wu, Peng-Hsiang Liao, Angela Yu-Huey Hsu, Li-An Chu, Ya-Ding Liu, Ya-Hui Lin, Yi-Cheng Tai, Chia-Tung Shun, Han-Mo Chiu, Ming-Shiang Wu. Mild chronic colitis triggers Parkinsonism in LRRK2 mutant mice through activating TNF-α pathway. Movement Disorders 2022 Apr;37(4):745-757. doi: 10.1002/mds.28890.
61. Yu-En Lin, Chin-Hsien Lin, En-Peng Ho, Yi-Ci Ke, Stavroula Petridi, Christopher J. H. Elliott, Lee-Yan Sheen,*, and Cheng-Ting Chien,* Gastrodia elata Blume prevents dopaminergic neuron degeneration via glial Nrf2 signaling in Lrrk2-G2019S Parkinson's disease models. eLife 2021. Nov 15;10:e73753. doi: 10.7554/eLife.73753.
62. Huan-Yun Chen, Chia-Lang Hsu, Han-Yi Lin, Yung-Feng Lin, Shih-Feng Tsai, Yu-Jung Ho, Ye-Ru Li, Jin-Wu Tsai, Shu-Chun Teng*, Chin-Hsien Lin*. Clinical and functional characterization of a novel STUB1 frameshift mutation in autosomal dominant spinocerebellar ataxia type 48 (SCA48). Journal of Biomedical Science 2021 Sep 26;28(1):65. doi: 10.1186/s12929-021-00763-1.
63. Chang KH, Huang CY, Ou-Yang CH, Ho CH, Lin HY, Hsu CL, Chen YZ, Chou YC, Yi-Jing Chen YJ, Chen Y, Lin JL,Wang KJ, Lin PW, Lin YR, Lin MH, Tseng CK, Lin CH*. In vitro genome editing rescues parkinsonism phenotypes in induced pluripotent stem cells-derived dopaminergic neurons carrying LRRK2 p.G2019S mutation. Stem Cell Research & Therapy 2021 Sep 22;12(1):508. doi: 10.1186/s13287-021-02585-2.
64. Yu-Chien Hung, Guan-Lin Huang, Po-Lin Chen, Jeng-Lin Li, Serena Huei-An Lu, Jui-Chih Chang, Han-Yi Lin, Wen-Chun Lo, Shu-Yi Huang, Tai-Ting Lee, Tai-Yi Lin, Yuzuru Imai, Nobutaka Hattori, Chin-San Liu, Su-Yi Tsai, Chun-Hong Chen, Chin-Hsien Lin,* Chih-Chiang Chan1.* UQCRC1 engages cytochrome c for neuronal apoptotic cell death. Cell Reports 2021 Sep 21;36(12):109729. doi: 10.1016/j.celrep.2021.109729.
65. Huang CW, Lin CH, Lin YH, Tsai HY, Tseng MT. Neural Basis of Somatosensory Spatial and Temporal Discrimination in Humans: The Role of Sensory Detection. Cereb Cortex. 2022 Mar 30;32(7):1480-1493.
66. Fan CH, Wei KC, Chiu NH, Liao EC, Wang HC, Wu RY, Ho YJ, Chan HL, Wang TA, Huang YZ, Hsieh TH, Lin CH, Lin YC*, Yeh CK*. Sonogenetic-Based Neuromodulation for the Amelioration of Parkinson's Disease. Nano Lett. 2021 Jul 28;21(14):5967-5976.
67. Pin-Shiuan Chen, Ni-Chung Lee, Sung-Pin Fan, Chun-Hwei Tai, Chang-Jin Huang, Wei-Hao Huang, Po-Wei Jeng, Jyh-Horng Chen, Chin-Hsien Lin.* Eye-of-tiger sign in globus pallidus: a novel radiological feature of spinocerebellar ataxia type 28. Movement Disorders, 2021, Sep;36(9):2200-2202.
68. Meng-Chen Wu, Yung-Yee Chang, Ying-Fa Chen, Min-Yu Lan, Pei-Lung Chen, Chun-Hwei Tai, Chin-Hsien Lin.* Investigating DYT1 in a Taiwanese dystonia cohort. Journal of the Formosan Medical Association, 2022 Jan;121(1 Pt 2):375-380.
69. Chiu MJ, Yang SY, Chen TF, Lin CH, Yang FC, Chen WP, Zetterberg H, Blennow K. Synergistic Association between Plasma Aβ1-42 and p-tau in Alzheimer's Disease but Not in Parkinson's Disease or Frontotemporal Dementia. ACS Chem Neurosci. 2021 Apr 7. doi: 10.1021/acschemneuro.1c00010.
70. Lin CH, Farrer MJ, Wu RM. Reply: UQCRC1 variants in Parkinson's disease: a large cohort study in the Chinese mainland. Brain. 2021 Mar 29:awab138. doi: 10.1093/brain/awab138. Online ahead of print.
71. Cheng-Hsuan Li, Ta-Fu Chen, Ming-Jang Chiu, Ruoh-Fang Yen, Ming-Chieh Shih, Chin-Hsien Lin.* Integrated 18F-T807 tau PET, structural MRI and plasma tau in tauopathy neurodegenerative disorders. Frontiers in Aging Neuroscience 2021 Mar 29;13:646440.
72. Fu-Cheng Wang *, Szu-Fu Chen, Chin-Hsien Lin, Wei Yuan, Chih-Jen Shih, Ang-Chieh Lin, You-Chi Li, Tien-Yun Kuo. Detection and Classification of Stroke Gaits by Deep Neural Networks Employing Inertial Measurement Units. Sensors 2021Mar 7;21(5):1864. doi: 10.3390/s21051864.
73. Hsin-Hsi Tsai, Li-Kai Tsai, Yen-Ling Lo, Chin-Hsien Lin.* Amyloid related cerebral microbleed and plasma Aβ40 are associated with cognitive decline in Parkinson’s disease. Scientific Reports 2021 Mar 29;11(1):7115. doi: 10.1038/s41598-021-86617-0.
74. Szu-Ju Chen, Yu-Chiao Chi, Chang-Han Ho, Wei-Shiung Yang, Chin-Hsien Lin.* Plasma lipopolysaccharide-binding protein reflects risk and progression of Parkinson’s disease. Journal of Parkinson’s disease 2021;11(3):1129-1139.
75. Jung-Lung Hsu^#, Chin-Hsien Lin^# (co-first), Pei-Lung Chen, Kun-Ju Lin, Ta-Fu Chen.* Genetic Study of Young-Onset Dementia Using Targeted Gene Panel Sequencing in Taiwan. American Journal of Medical Genetics Part B 2021, Feb 13. doi: 10.1002/ajmg.b.32836.
76. Chih-Hsin Ou-Yang, Chun-Hwei Tai, Han-Yi Lin, Cheng-Yen Huang, Chin-Hsien Lin.* Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-070-02) from a patient with neurodegeneration with brain iron accumulation (NBIA) having compound heterozygous mutations in PANK2 gene. Stem Cell Research 2021, in press. Stem Cell Res 2021 Mar;51:102190. doi: 10.1016/j.scr.2021.102190.
77. Chin-Hsien Lin*^#, Chin-Hao Chang^#, Chun-Hwei Tai, Mei-Fang Cheng, Yi-Chieh Chen, Ying-Ting Chao, Tse-Le Huang, Ruoh-Fang Yen, Ruey-Meei Wu. A Double-Blind Randomized Controlled Trial of Lovastatin in Early-Stage Parkinson’s Disease. Movement Disorders, 2021 May;36(5):1229-1237.
78. Han-Yi Lin, Chih-Hsin Ou-Yang, Chin-Hsien Lin*. Reprogramming of a human induced pluripotent stem cell (iPSC) line from a patient with neurodegeneration with brain iron accumulation (NBIA) harboring a novel frameshift mutation in C19orf12 gene. Stem Cell Research 2020, Oct 14;49:102032. doi: 10.1016/j.scr.2020.102032.
79. Chih-Hsin Ou-Yang, Han-Yi Lin, Cheng-Yen Huang, Chin-Hsien Lin*. Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-057-05) from a patient with familial parkinsonism and polyneuropathy having a heterozygous p.Y314S mutation in UQCRC1 gene. Stem Cell Research 2020 Oct 10;49:102031. doi: 10.1016/j.scr.2020.102031.
80. Chin-Hsien Lin, Shu-I Chiu, Ta-Fu Chen, Jyh-Shing Roger Jang, Ming-Jang Chiu*. Classifications of Neurodegenerative Disorders Using a Multiplex Blood
    Biomarkers-Based Machine Learning Model. International Journal of Molecular Sciences, 2020 Sep 21;21(18):E6914.
81. Chin-Hsien Lin*, Han-Yi Lin, Jim-Min Fang, Ching-Chow Chen*. A dual inhibitor targeting HMG-CoA reductase and histone deacetylase mitigates neurite degeneration in LRRK2-G2019S parkinsonism. Aging (Albany NY)-US. 2020 Nov 24;12(24):25581-25598.
82. Szu-Ju Chen, Chang-Han Ho, Hang-Yi Lin, Chin-Hsien Lin*, Ruey-Meei Wu. Lack of PTRHD1 mutation in patients with young-onset and familial Parkinson’s disease in a Taiwanese population. Neurobiology of Aging, 2020 Sep 8;S0197-4580(20)30279-7.
83. Huan-Yun Chen, Chin-Hsien Lin*, Shu-Chun Teng* Stress-induced p53 drives BAG5 cochaperone expression to control α-synuclein aggregation in Parkinson's disease. Aging (Albany NY), 2020 Oct 21;12(20):20702-20727.
84. Szu-Ju Chen, Ching-Hua Kuo, Han-Chun Kuo, Chieh-Chang Chen, Wei-Kai Wu, Jyh-Ming Liou, Ming-Shiang Wu, Chin-Hsien Lin*. The gut metabolite trimethylamine N-oxide is associated with Parkinson’s disease severity and progression. Movement Disorders 2020 Nov;35(11):2115-2116.
85. Chin-Hsien Lin, Pei-I Tsai, Han-Yi Lin, Nobutaka Hattori, Manabu Funayama, Beomseok Jeon, Kota Sato, Koji Abe, Yohei Mukai, Yuji Takahashi, Yuanzhe Li, Kenya Nishioka, Hiroyo Yoshino, Kensuke Daida, Meng-Ling Chen, Jay Cheng, Cheng-Yen Huang, Shiou-Ru Tzeng, Yen-Sheng Wu, Hsing-Jung Lai, Hsin-Hsi Tsai, Ruoh-Fang Yen, Ni-Chung Lee, Wen-Chun Lo, Yu-Chien Hung, Chih-Chiang Chan, Yi-Ci Ke, Chi-Chao Chao, Sung-Tsang Hsieh, Matthew Farrer,* Ruey-Meei Wu* Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy. Brain 2020 Dec 5;143(11):3352-3373.
86. Szu-Ju Chen, Bo-Chin Lee, Ni-Chung Lee, Yin-Hsiu Chien, Wuh-Liang Hwu, Chin-Hsien Lin*. Clinical, radiological and genetic characteristics in patients with Huntington’s Disease in a Taiwanese cohort. American Journal of Medical Genetics Part B 2020 Sep;183(6):352-359.
87. Sung-Pin Fan, Ni-Chung Lee, Chin-Hsien Lin*. Novel phenotype of 6p25 deletion syndrome presenting juvenile parkinsonism and brain calcification. Movement Disorders 2020 Aug;35(8):1457-1462.
88. Huei-Chun Liu, Ming-Jang Chiu, Chin-Hsien Lin, Shieh-Yueh Yang*. Stability of Plasma Amyloid-β 1–40, Amyloid-β 1–42, and Total Tau Protein over Repeated Freeze/Thaw Cycles. Dement Geriatr Cogn Disord Extra 2020 Mar 26;10(1):46-55.
89. Yung-Tsai Chu, Han-Yi Lin, Pei-Lung Chen, Chin-Hsien Lin*. Genotype-Phenotype Correlations of adult-onset PLA2G6-Associated Neurodegeneration: Case series and literature review. BMC Neurology 2020, Mar 17;20(1):101. doi: 10.1186/s12883-020-01684-6.
90. Han-Yi Lin, Li-Kai Tsai, Yu-Che Cheng, Huai-En Lu, Ching-Ying Huang, Patrick C.H. Hsieh, Chin-Hsien Lin*. Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-048-05) from a patient with ALS and parkinsonism having a hexanucleotide repeat expansion mutation in C9orf72 gene. Stem Cell Research 2020 Feb 27;44:101734. doi: 10.1016/j.scr.2020.101734
91. Cheng-Hsuan Li, Sung-Pin Fan, Ta-Fu Chen, Ming-Jang Chiu, Ruoh-Fang Yen, Chin-Hsien Lin*. Frontal variant of Alzheimer’s disease with asymmetric presentation mimicking frontotemporal dementia: case report and literature review. Brain and Behavior 2020 Mar;10(3):e01548. doi: 10.1002/brb3.1548. Epub 2020 Jan 27.
92. Yi-Cheng Tai, Chin-Hsien Lin*. An Overview of Pain in Parkinson’s disease. Clinical Parkinsonism & Related Disorders, 2020; 2: 1-8.
93. Chih-Hao Chen, Bo-Ching Lee, Chin-Hsien Lin*. Integrated plasma and neuroimaging biomarkers associated with motor and cognition severity in Parkinson’s disease. Journal of Parkinson’s disease, 2020;10(1):77-88.
94. Lin CH, Liu HC, Yang SY, Yang KC, Wu CC, Chiu MJ. Plasma pS129-α-Synuclein Is a Surrogate Biofluid Marker of Motor Severity and Progression in Parkinson's Disease. J Clin Med. 2019 Oct 3;8(10). pii: E1601. doi: 10.3390/jcm8101601.
95. Szu-Ju Chen, Ni-Chung Lee, Yin-Hsiu Chien, Wuh-Liang Hwu, Chin-Hsien Lin* Heterogeneous non-ataxic phenotypes of spinocerebellar ataxia in a Taiwanese population. Brain and Behavior 2019, Oct;9(10):e01414. doi: 10.1002/brb3.1414. Epub 2019 Sep 16.
96. Tung-Hung Su, Hung-Chih Yang, Tai-Chung Tseng, ShihWan Chou, Chin-Hsien Lin, Chen-Hua Liu, Chun-Jen Liu, Chi-Ling Chen*, Jia-Horng Kao*. Antiviral therapy in patients with chronic hepatitis C is associated with a reduced risk of parkinsonism. Movement Disorders 2019 Sep 10. 34(12):1882-1890.
97. Szu-Ju Chen; Ruey-Meei Wu; Chang-Han Ho; Jay Cheng; Han-I Lin; Chin-Hsien Lin*. Genetic analysis of PODXL gene in patients with familial and young onset Parkinson's disease in a Taiwanese population. Neurobiology of Aging 2019 Sep 8. pii: S0197-4580(19)30306-9. doi: 10.1016/j.neurobiolaging.2019.08.027.
98. Sung-Pin Fan, Ni-Chung Lee, Chin-Hsien Lin*. Clinical and electrophysiological characteristics of a type I sialidosis patient with a novel deletion mutation in NEU1: case report and review of the literature. Journal of the Formosan Medical Association 2019, Jul 29. pii: S0929-6646(19)30332-8. doi: 10.1016/j.jfma.2019.07.017.
99. Vollstedt EJ, Kasten M, Klein C; MJFF Global Genetic Parkinson's Disease Study Group; Aasly J, Adler C, Ahmad-Annuar A, Albanese A, Alcalay R, Al-Mubarak B, Alvarez V, Andree-Muñoz B, Annesi G, Appel-Cresswell S, Arkadir D, Armasu S, Barber TR, Bardien S, Barkhuizen M, Barrett MJ, BaŞak AN, Beach T, Benitez BA, Berg D, Bhatia K, Binkofski F, Blauwendraat C, Bonifati V, Borges V, Bozi M, Brice A, Brighina L, Brockmann K, Brüggemann N, Camacho M, Cardoso F, Belin AC, Carr J, Chan P, Chang-Castello J, Chase B, Chen-Plotkin A, Chung SJ, Cilia R, Clarimon J, Clark L, Cornejo-Olivas M, Corvol JC, Cosentino C, Cras P, Crosiers D, Damásio J, Das P, de Carvalho Aguiar P, De Michele G, De Rosa A, Dieguez E, Dorszewska J, Erer S, Ertan S, Farrer M, Fedotova E, Ferese R, Ferrarese C, Ferraz H, Fiala O, Foroud T, Friedman A, Frigerio R, Funayama M, Gambardella S, Garraux G, Gatto EM, Genç G, Goldwurm S, Gomez-Esteban JC, Gómez-Garre P, Gorostidi A, Grosset D, Hanagasi H, Hardy J, Hassan A, Hattori N, Hauser RA, Hedera P, Hentati F, Hertz JM, Holton JL, Houlden H, Hutz MH, Ikeuchi T, Illarioshkin S, Inca-Martinez M, Infante J, Jankovic J, Jeon BS, Jesús S, Jimenez-Del-Rio M, Kasten M, Kataoka H, Kawakami H, Kim YJ, Klein C, Klivényi P, Koks S, König IR, KostiĆ V, Koziorowski D, Krüger R, Krygowska-Wajs A, Kulisevsky J, Lang A, LeDoux M, Lesage S, Lim SY, Lin CH, Lohmann K, Lopera F, Lopez G, Lu CS, Lynch T, Machaczka M, Madoev H, Magalhães M, Majamaa K, Maraganore D, Marder K, Markopoulou K, Martikainen MH, Mata I, Mazzetti P, Mellick G, Menéndez-González M, Micheli F, Mirelman A, Mir P, Morino H, Morris H, Munhoz RP, Naito A, Olszewska DA, Ozelius LJ, Padmanabhan S, Paisán-Ruiz C, Payami H, Peluso S, Petkovic S, Petrucci S, Pezzoli G, Pimentel M, Pirker W, Pramstaller PP, Pulkes T, Puschmann A, Quattrone A, Raggio V, Ransmayr G, Rieder C, Riess O, Rodriguez-Porcel F, Rogaeva E, Ross OA, Ruiz-Martinez J, Sammler E, Luciano MS, Satake W, Saunders-Pullman R, Sazci A, Scherzer C, Schrag A, Schumacher-Schuh A, Sharma M, Sidransky E, Singleton AB, Petersen MS, Smolders S, Spitz M, Stefanis L, Struhal W, Sue C, Swan M, Swanberg M, Taba P, Taipa R, Tan M, Tan AH, Tan EK, Tang B, Tayebi N, Thaler A, Thomas A, Toda T, Toft M, Torres L, Tumas V, Valente EM, Van Broeckhoven C, Vecsei L, Velez-Pardo C, Vidailhet M, Vollstedt EJ, Warner TT, Williams-Gray CH, Winkelmann J, Woitalla D, Wood NW, Wszolek ZK, Wu RM, Wu YR, Xie T, Yoshino H, Zhang B, Zimprich A. Using global team science to identify genetic Parkinson's disease worldwide. Ann Neurol 2019 Aug;86(2):153-157.
100. Chin-Hsien Lin*, Chieh-Chang Chen, Han-Lin Chiang, Jyh-Ming Liou, Chih-Min Chang, Tzu-Pin Lu, Eric Y Chuang, Yi-Cheng Tai, Chieh Cheng, Han-Yi Lin, Ming-Shiang Wu. Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease. Journal of Neuroinflammation 2019 Jun 27;16(1):129. doi: 10.1186/s12974-019-1528-y.
101. Chin-Hsien Lin, Cheng-Hsuan Li, Kai-Chien Yang, Fang-Ju Lin, Chau-Chung Wu, Jen-Jie Chieh, and Ming-Jang Chiu. Blood NfL: A biomarker for disease severity and progression in Parkinson’s disease. Neurology 2019 Sep 10;93(11):e1104-e1111.
102. Yih-Chih Kuo, Chin-Hsien Lin*. Clinical spectrum of glutamic acid decarboxylase antibodies in a Taiwanese population. European Journal of Neurology 2019, Nov;26(11):1384-1390.
103. Han-Lin Chiang, Chin-Hsien Lin*. Altered gut microbiome and intestinal pathology in Parkinson’s disease. Journal of Movement Disorders 2019 May;12(2):67-83. doi: 10.14802/jmd.18067. Epub 2019 May 30.
104. Han-I Lin, Yu-Che Cheng, Hui-Wen Ko, Cheng-Hao Wen, Huai-En Lu, Ching-Ying Huang*, Patrick C.H. Hsieh*, Chin-Hsien Lin*. Generation of induced pluripotent stem cells (IBMSi011-A) from a patient with Parkinson's disease carrying LRRK2 p.I1371V mutation. Stem Cell Research 2019 May;37:101447. doi: 10.1016/j.scr.2019.101447. Epub 2019 Apr 22.
105. Yu-Che Cheng, Han-I Lin, Shih-Han Syu, Huai-En Lu, Ching-Ying Huang^*, Chin-Hsien Lin^*, Patrick C.H. Hsieh^*. Reprogramming of a human induced pluripotent stem cell (iPSC) line (IBMSi012-A) from an early-onset Parkinson's disease patient harboring a homozygous p.D331Y mutation in the PLA2G6 gene. Stem Cell Research 2019 Apr 5;37:101432. doi: 10.1016/j.scr.2019.101432.
106. Ming-Che Kuo, Han-I Lin, Chin-Hsien Lin^*. Craniocervical dystonia with levodopa-responsive parkinsonism co-segregating with a pathogenic ANO3 mutation in a Taiwanese family. Parkinsonism and Related Disorders 2019 May;62:236-238.
107. Chin-Hsien Lin, Pei-Lung Chen, Chun-Hwei Tai, Hang-I Lin, Chih-Shan Chen, Meng-Ling Chen, Ruey-Meei Wu^*. A clinical and genetic study of early-onset and familial parkinsonism in Taiwan: an integrated approach combining gene dosage analysis and next generation sequencing. Movement Disorders 2019 Apr;34(4):506-515.
108. Chun-Fu Lai, Yen-Ting Chen, Jian Gu, Jeanne M. Nerbonne, Chin-Hsien Lin*, Kai-Chien Yang*. Circulating long noncoding RNA DKFZP434I0714 predicts adverse cardiovascular outcomes in patients with end-stage renal disease. International Journal of Cardiology 2019 Feb 15;277:212-219.